在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LMTK2 Antibody

LMTK2 Antibody

  • 中文名稱：
    LMTK2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA008263
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of LOVO cells using KPI-2 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    LMTK2
  • 別名：
    AATYK 2 antibody; AATYK2 antibody; Apoptosis associated tyrosine kinase 2 antibody; Apoptosis-associated tyrosine kinase 2 antibody; Brain enriched kinase antibody; Brain-enriched kinase antibody; BREK antibody; CDK5/p35 regulated kinase antibody; CDK5/p35-regulated kinase antibody; CPRK antibody; cyclin-dependent kinase 5/p35-regulated kinase antibody; FLJ46659 antibody; hBREK antibody; KIAA1079 antibody; Kinase phosphatase inhibitor 2 antibody; Kinase/phosphatase/inhibitor 2 antibody; KPI 2 antibody; KPI-2 antibody; KPI2 antibody; Lemur tyrosine kinase 2 antibody; LMR 2 antibody; LMR2 antibody; LMTK 2 antibody; Lmtk2 antibody; LMTK2_HUMAN antibody; PPP1R100 antibody; protein phosphatase 1; regulatory subunit 100 antibody; Serine/threonine protein kinase KPI 2 antibody; Serine/threonine protein kinase KPI2 antibody; Serine/threonine protein kinase LMTK 2 antibody; Serine/threonine protein kinase LMTK2 antibody; Serine/threonine-protein kinase KPI-2 antibody; Serine/threonine-protein kinase LMTK2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human KPI-2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Phosphorylates PPP1C, phosphorylase b and CFTR.
  • 基因功能參考文獻(xiàn)：
    1. both BIM and BCL2 proteins are regulated by LMTK2 in a GSK3beta- and PP1A-dependent manner. PMID: 28040547
    2. Mutation of the di-acidic export motif led to endoplasmic reticulum retention of LMTK2, and an increase in protein half-life. PMID: 26559041
    3. Lemur Tyrosine Kinase-2 (LMTK2), negatively regulates androgen-dependent and androgen-independent prostate cancer cell proliferation. In addition, LMTK2 also negatively regulates the androgen receptor transcriptional activity. PMID: 26008968
    4. Data indicate that Lemur tyrosine kinase 2 (LMTK2) localizes at the plasma membrane and co-immunoprecipitates with cystic fibrosis transmembrane conductance regulator (CFTR) in airway epithelial cells. PMID: 24727471
    5. The results indicate that lemur tyrosine kinase 2 is an integral membrane protein in which both the amino and carboxyl termini are exposed to the cytoplasm. Moreover, this topology places the kinase active site within the cytoplasm. PMID: 23114966
    6. We describe a new signalling pathway within the nervous system that links cdk5/p35 with phosphatase-1C and which has implications for a number of neuronal functions and neuronal dysfunction PMID: 22220831
    7. Low LMTK2 expression is associated with the development of prostate cancer. PMID: 20569440
    8. KPI-2 is a kinase with sites to associate with PP1C and Inh2 to form a regulatory complex that is localized to membranes PMID: 12393858
    9. Cprk is expressed in a number of tissues but is enriched in brain and muscle; Cprk displays catalytic activity in kinase assays and is itself phosphorylated by cdk5/p35; Cdk5/p35 inhibits cprk activity PMID: 12832520
    10. BREK, Brain Enriched Kinase, is a new member of the family of protein serine/threonine kinases; plays important roles in NGF-TrkA signalling in the brain [BREK] PMID: 15005709
    11. role of the segment KLHY in binding with protein phosphatase 1 PMID: 16428298
    12. Myosin VI and LMTK2 are required for the transport of cargo, such as the Transferrin Receptor, from early endosomes to the endocytic recycling compartment. PMID: 18029400
    13. Results show that BREK is critical for the transition of endocytosed membrane vesicles from early endosomes to recycling endosomes and also suggest an involvement of myosin VI in this pathway. PMID: 18429820

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Protein kinase superfamily, Tyr protein kinase family
  • 組織特異性：
    Mainly expressed in skeletal muscle, and weakly in brain and pancreas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17880

    OMIM: 610989

    KEGG: hsa:22853

    STRING: 9606.ENSP00000297293

    UniGene: Hs.444179



主站蜘蛛池模板： 14萝自慰专用网站| 欧美孕妇变态重口另类| 男人av无码天堂| 亚洲中文色欧另类欧美| 亚洲精品v天堂中文字幕| 男女性潮高清免费网站| 国产成久久免费精品av片| 综合色就爱涩涩涩综合婷婷| 亚洲色欲色欲大片www无码| 欧美成人免费一区二区| 国产区图片区小说区亚洲区| 久久无码潮喷a片无码高潮 | 久久久婷婷五月亚洲97号色| 久章草在线精品视频免费观看| 欧美成aⅴ人高清免费| 国内精品视频一区二区八戒| 亚洲国产精久久久久久久| 国产精品无码久久av| 熟妇人妻无码中文字幕老熟妇 | 蜜桃av麻豆av果冻传媒| 日韩夜夜高潮夜夜爽无码| 亚洲18色成人网站www| 人妻免费一区二区三区最新| 国产1卡2卡3卡4卡免费| 亚洲一卡2卡3卡4卡精品 | 色琪琪丁香婷婷综合久久| 粉色午夜视频| 国产精品午夜福利视频234区| 高清粉嫩无套内谢国语播放| 亚洲人禽杂交av片久久| 国产精品玩偶在线观看| 成人性做爰aaa片免费看不忠| 香蕉成人伊视频在线观看| 亚洲欧美综合一区二区三区| av性色av久久无码ai换脸| 成人免费无码大片a毛片| 免费视频欧美无人区码| 亚洲 欧美 另类图片| 琪琪午夜理论片福利在线观看 | 亚洲人成小说网站色在线观看| 欧美日韩综合一区二区三区|