在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LMNB2 Antibody, FITC conjugated

  • 中文名稱:
    LMNB2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA013005LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LMNB2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    LAMB 2 antibody; LAMB2 antibody; Lamin-B2 antibody; LMN 2 antibody; LMN B2 antibody; LMN2 antibody; LMNB 2 antibody; LMNB2 antibody; LMNB2_HUMAN antibody; MGC2721 antibody; RGD1563803 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Lamin-B2 protein (442-615AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
  • 基因功能參考文獻:
    1. our studies strongly implicate an overarching role for Lamin B2 in the maintenance of nuclear architecture since loss of Lamin B2 relieves the spatial positional constraints required for maintaining conserved localization of aneuploid chromosome territories in the interphase nucleus. PMID: 26921073
    2. Mutation of the nuclear lamin gene LMNB2 in progressive myoclonus epilepsy with early ataxia. PMID: 25954030
    3. Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform. PMID: 25477337
    4. Treating normal human fibroblasts with farnesyltransferase inhibitors causes the accumulation of unprocessed lamin B2 and lamin A and a decrease in mature lamin B1 PMID: 23475125
    5. Mutation in LMNB2 gene is associated with partial lipodystrophy. PMID: 22768673
    6. Studies indicate that the lamin-binding proteins implicated in laminopathies include lamin B2 and nuclear envelope proteins. PMID: 21400569
    7. These findings indicate that a lamin dimer principally has the freedom for a "combinatorial" head-to-tail association with all types of lamins, a property that might be of significant importance for the assembly of the nuclear lamina. PMID: 20004208
    8. analysis of protein-DNA interactions at the human lamin B2 replication origin PMID: 12902329
    9. The proteins bound in vivo at the LMNB2 replication origin were investigated along the cell cycle. PMID: 12912926
    10. This analysis reveals the modular structure of the lamin B2 origin and supports the idea that sequence elements close to the replication start site play an important role in origin activation. PMID: 15024083
    11. the distinctive ensemble of heterotypic lamin interactions in a particular cell type affects the stability of the lamin polymer PMID: 15284226
    12. the lamin B2 origin adopts a structure partly composed of intramolecular TAT triads PMID: 15611042
    13. lamin B was essential for the formation of the mitotic matrix that tethers a number of spindle assembly factors; propose that lamin B is a structural component of the spindle matrix that promotes microtubule assembly and organization in mitosis PMID: 16543417
    14. Three new rare heterozygous mutations are the first reported for LMNB2 and are the first reported among patients with acquired partial lipodystrophy. PMID: 16826530
    15. human lamin B(2) is indeed synthesized as a longer version than previously reported, because it contains these additional 20 amino acids PMID: 17070523
    16. The human DNA replication origin, located in the lamin B2 gene, interacts with the DNA topoisomerases I and II in a cell cycle-modulated manner. PMID: 17290216

    顯示更多

    收起更多

  • 相關疾病:
    Partial acquired lipodystrophy (APLD); Epilepsy, progressive myoclonic 9 (EPM9)
  • 亞細胞定位:
    Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
  • 蛋白家族:
    Intermediate filament family
  • 數據庫鏈接:

    HGNC: 6638

    OMIM: 150341

    KEGG: hsa:84823

    STRING: 9606.ENSP00000462730

    UniGene: Hs.538286



主站蜘蛛池模板: 成人毛片一区二区| 国产大学生粉嫩无套流白浆| 国精产品一区二区三区有限公司| 97人妻精品一区二区三区| 欧美大屁股流白浆xxxx| 国产性―交―乱―色―情人| 亚洲色欲色欲综合网站| 男女后进式猛烈xx00动态图片| 国产欧美另类久久精品蜜芽| 欧美日韩国产亚洲沙发| 中文无码精品a∨在线| 无码人妻一区二区三区在线| 亚洲最大日夜无码中文字幕| 玩肥熟老妇bbw视频| 国产成_人_综合_亚洲_国产| 波多野结衣在线观看一码| 中文字幕一区二区三区精华液| 日本高清在线www3344| 又大又紧又粉嫩18p少妇 | 交换交换乱杂烩系列yy| 中国少妇videos呻吟| 国产成人av一区二区三区在线观看| 老熟妇高潮喷了╳╳╳| 欧美成aⅴ人高清怡红院| 先锋影音av最新资源网| 一区二区视频| 国内偷自第一区二区三区| 国产精品美女久久久m| 亚洲性猛交xxxx| 成人午夜精品无码区| 国产毛片不卡野外视频| 天天爽夜夜爽人人爽免费| 少妇下面好紧好多水真爽播放| 又色又爽又高潮免费观看| 国产乱子伦一区二区三区四区五区| 国产丰满老熟妇乱xxx1区| 成 人 在 线 免费观看| 成 人 网 站94免费观看| 免费观看一区二区三区| 精品国产精品三级精品av网址| av毛片无码中文字幕不卡|