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  4. LMCD1 Antibody, FITC conjugated

LMCD1 Antibody, FITC conjugated

  • 中文名稱：
    LMCD1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA873714LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LMCD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LMCD1
  • 別名：
    Dyxin antibody; LIM and cysteine rich domains 1 antibody; LIM and cysteine rich domains protein 1 antibody; LIM and cysteine-rich domains protein 1 antibody; LMCD1 antibody; LMCD1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LIM and cysteine-rich domains protein 1 protein (105-268AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
  • 基因功能參考文獻：
    1. The rs1800775 [1.31 (1.22-1.42); p = 3.41E-12] in the CETP gene and rs359027 [1.26 (1.16-1.36); p = 2.55E-08] in the LMCD1 gene were significantly associated with LHDLC levels PMID: 26879886
    2. Together, our results suggest that LMCD1 mutations are potential oncogenic events in HCC metastasis to promote cell migration through the Rac1-signaling pathway. PMID: 21996735
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 組織特異性：
    Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle.
  • 數據庫鏈接：

    HGNC: 6633

    OMIM: 604859

    KEGG: hsa:29995

    STRING: 9606.ENSP00000157600

    UniGene: Hs.475353



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