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  4. LHX6 Antibody

LHX6 Antibody

  • 中文名稱：
    LHX6兔多克隆抗體
  • 貨號：
    CSB-PA891795ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA891795ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LHX6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LHX6
  • 別名：
    LHX 6 antibody; LHX 6.1 antibody; LHX6 antibody; LHX6.1 antibody; LHX6_HUMAN antibody; LIM homeobox 6 antibody; LIM homeobox protein 6 antibody; LIM homeodomain protein 6.1 antibody; LIM/homeobox protein Lhx6 antibody; LIM/homeobox protein Lhx6.1 antibody; MGC119542 antibody; MGC119544 antibody; MGC119545 antibody; OTTHUMP00000064113 antibody; OTTHUMP00000064114 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LIM/homeobox protein Lhx6 protein (114-363AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
  • 基因功能參考文獻：
    1. that down-regulation of miR-214 may reverse acquired resistance to erlotinib in NSCLC through mediating its direct target gene LHX6 expression. PMID: 28396596
    2. LHX6 inhibits breast cancer cell proliferation and invasion via repression of the Wnt/beta-catenin signaling pathway. PMID: 26129710
    3. LHX6 is a putative tumour suppressor gene with epigenetic silencing in lung cancer. PMID: 24157876
    4. LHX6 is a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis PMID: 23229549
    5. found positive association of LHX6 with Tourette syndrome in some European populations, not others. LHX6 demonstrates a high degree of population differentiation and is correlated with the North to South axis of European genetic variation. PMID: 22435649
    6. hLHX6.1 could be a new tumor suppressor gene in the cervix. PMID: 21240459
    7. Hypermethylation of LHX6 is associated with cervical cancer. PMID: 20428825
    8. differentially methylated hypermethylation of LHX6 is a good cancer marker in HNSCC as well as in other kinds of neoplasias and confirm the importance of searching for markers of epigenetic dysregulation in cancer PMID: 16732332

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  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 21735

    OMIM: 608215

    KEGG: hsa:26468

    STRING: 9606.ENSP00000377854

    UniGene: Hs.103137



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