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LHX2 Antibody, Biotin conjugated

  • 中文名稱:
    LHX2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA012920LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LHX2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    LHX2
  • 別名:
    hLhx2 antibody; Homeobox protein LH-2 antibody; Homeobox protein LH2 antibody; LH2 antibody; LHX2 antibody; LHX2_HUMAN antibody; LIM homeobox 2 antibody; LIM homeobox protein 2 antibody; LIM HOX gene 2 antibody; LIM/homeobox protein Lhx2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human LIM/homeobox protein Lhx2 protein (197-377AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types.
  • 基因功能參考文獻:
    1. These data indicate that Lhx2 is capable of blocking proliferation of T-ALL-derived cells by both LMO2-dependent and -independent means. We propose Lhx2 as a new molecular tool for anti-T-ALL drug development. PMID: 29278703
    2. Findings demonstrate that miR-1238 inhibit the proliferation of NSCLC cells at least partly via repression of LHX2, shedding light on the mechanistic interaction of miR-1238 and LHX2 in NSCLC carcinogenesis. PMID: 26189214
    3. Results show that LHX2 is overexpressed in pancreatic ductal adenocarcinoma cells and is involved in promoting cancer cell proliferation and enhanced tumor development. PMID: 25324171
    4. Lhx2 directly regulates tanycyte specification and differentiation in the hypothalamus. PMID: 25505333
    5. This study demonistrated that LHx2 regulates the development of the forebrain hem system. PMID: 23307637
    6. The data indicate a dual role of Lhx2 during EMT and tumor progression: by inducing the expression of PDGF-B, Lhx2 provokes an autocrine PDGF-B/PDGFRbeta loop required for cell migration, invasion and metastatic dissemination PMID: 24423492
    7. The findings indicate that LHX2 regulates the transcription of downstream intrinsic and extrinsic molecules that are essential for early neural differentiation. PMID: 23804753
    8. These results suggest that if LHX2 is involved in pituitary hormone deficiency associated with posterior pituitary and ocular defects, it would be a rare cause of this disease condition. PMID: 22535646
    9. Mutations in LHX2 do not represent a frequent cause of micro/anophthalmia. PMID: 21203406

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  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 6594

    OMIM: 603759

    KEGG: hsa:9355

    STRING: 9606.ENSP00000362717

    UniGene: Hs.696425



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