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LHPP Antibody

  • 中文名稱:
    LHPP兔多克隆抗體
  • 貨號:
    CSB-PA867114HA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA867114HA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LHPP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ44846 antibody; FLJ46044 antibody; HDHD2B antibody; hLHPP antibody; lhpp antibody; LHPP_HUMAN antibody; Phospholysine phosphohistidine inorganic pyrophosphate phosphatase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein (1-270AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,LHPP Antibody (CSB-PA867114HA01HU),的標記方式是Non-conjugated。對于LHPP Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA867114HB01HU LHPP Antibody, HRP conjugated ELISA
    FITC CSB-PA867114HC01HU LHPP Antibody, FITC conjugated
    Biotin CSB-PA867114HD01HU LHPP Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency.
  • 基因功能參考文獻:
    1. LHPP suppresses cell proliferation and metastasis in cervical cancer, and promotes apoptosis by suppressing AKT activation. PMID: 29944886
    2. in patients with hepatocellular carcinoma, low expression of LHPP correlated with increased tumour severity and reduced overall survival; thus LHPP is a protein histidine phosphatase and tumour suppressor, suggesting that deregulated histidine phosphorylation is oncogenic PMID: 29562234
    3. LHPP is associated with the interplay of risky sexual behaviors and alcohol dependence. PMID: 27531626
    4. Patients with major depressive disorder with LHPP rs35936514 CT/TT genotype have increased activity in certain brain regions. PMID: 27843651
    5. LHPP gene variation is associated with oral cavity and pharyngeal cancer. PMID: 27749845
    6. Lhpp or a product of a collinear brain-specific transcript, therefore, may interact with Htr1a in the pathogenesis of major depression PMID: 18268499

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  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    HAD-like hydrolase superfamily
  • 組織特異性:
    Expressed in brain, and at lower levels in liver and kidney. Detected in thyroid (at protein level). Expressed in liver, kidney and moderately in brain.
  • 數據庫鏈接:

    HGNC: 30042

    OMIM: 617231

    KEGG: hsa:64077

    STRING: 9606.ENSP00000357835

    UniGene: Hs.527748



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