在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LGALS4 Antibody, FITC conjugated

  • 中文名稱:
    LGALS4兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA012889LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LGALS4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    LGALS4
  • 別名:
    Antigen NY CO 27 antibody; Antigen NY-CO-27 antibody; Antigen NYCO27 antibody; GAL 4 antibody; Gal-4 antibody; GAL4 antibody; Galectin 4 antibody; Galectin-4 antibody; Galectin4 antibody; Homo sapiens galectin4 mRNA complete cds antibody; L 36 lactose binding protein antibody; L-36 lactose-binding protein antibody; L36 lactose binding protein antibody; L36LBP antibody; Lactose binding lectin 4 antibody; Lactose-binding lectin 4 antibody; Lectin galactoside binding soluble 4 antibody; LEG4_HUMAN antibody; LGALS4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Galectin-4 protein (1-323AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.
  • 基因功能參考文獻:
    1. Data show that galectin-4 expressing tumor cells interact directly with red blood cells (RBCs). PMID: 28293788
    2. Haplotype formed from two promoter SNPs rs116896264 and rs73933062 is associated with galectin-4 overexpression in colorectal cancer. PMID: 26681582
    3. LGALS4 may function as a tumor suppressor gene in UC progression. Findings provide evidence that methylation-mediated LGALS4 gene repression may be involved in urothelial tumor progression. PMID: 28423602
    4. Together, the data demonstrated that surface-bound galectin-4 is a dual function protein-down-regulating cell proliferation and chemokine secretion in galectin-4-expressing colorectal cancer cells on one hand and inducing apoptosis in galectin-4-negative colorectal cancer cells on the other hand. PMID: 28345468
    5. The carbohydrate-binding site is composed of residues His236, Asn238, Arg240, Asn249, Trp256, Glu259 and Lys261 at the strands S4, S5 and S6. PMID: 26432949
    6. The data suggests that arm-Gal4 has detrimental effects on Drosophila development and lifespan that are directly dependent upon parental inheritance PMID: 26505429
    7. The co-expression of galectin-4 and CNT3 proteins is not impaired in inflamed colon from patients with Crohn's disease, thereby anticipating the integrity of this system for drug targeting. PMID: 26481311
    8. Structural characterization of human galectin 4 C-terminal domain in terms its ligands binding specificity has been reported. PMID: 26077389
    9. role in basolateral to apical epithelial transcytosis PMID: 25179596
    10. The results show galectin-4 expression closely associates with hepatocellular carcinoma (HCC) progression and might have potential use as a prognostic biomarker for HCC patients. PMID: 25230111
    11. Galectin-4 plays an important role in metastatic process of lung adenocarcinoma. PMID: 24339976
    12. Data indicate that galectin-4 elicits tumor promotion in vitro and in vivo through activation of IL-6/NF-kappaB/STAT3 signaling. PMID: 23378274
    13. Loss of Galectin-4 is associated with colorectal cancer. PMID: 21064109
    14. crystals of galectin-4 belonged to space group P6(1)22, with unit-cell parameters a = b = 71.25, c = 108.66 A. PMID: 20445255
    15. microarray study in sinonasal adenocarcinoma we identified proteins, LGALS4 that is significantly differentially expressed in tumors compared to normal tissue PMID: 19903339
    16. results suggest that galectin-4 has a unique carbohydrate binding specificity and interacts with O-linked sulfoglycans PMID: 11971864
    17. SB1a and CEA in the patches on the cell surface of human colon adenocarcinoma cells could be biologically important ligands for galectin-4 PMID: 15546874
    18. Together, our data propose that interaction between galectin-4 and sulfatides plays a functional role in the clustering of lipid rafts for apical delivery. PMID: 15883199
    19. Galectin 4 induces surface phosphatidylserine exposure in a carbohydrate-dependent fashion in activated, but not resting, human neutrophils and in several leukocyte cell lines. PMID: 16940423
    20. not only sulfated glycosphingolipids but also cholesterol 3-sulfate are endogenous ligands for galectin-4 in vivo PMID: 17545668
    21. chemical analysis of talose-selectivity of galectin-4 and galectin-8 PMID: 18539029
    22. Data show that the pattern of N-glycosylation of glycoproteins serves as a recognition signal for endocytosed galectin-4, which drives the raft-dependent apical pathway of glycoproteins in enterocyte-like HT-29 cells. PMID: 19192249

    顯示更多

    收起更多

  • 數據庫鏈接:

    HGNC: 6565

    OMIM: 602518

    KEGG: hsa:3960

    STRING: 9606.ENSP00000302100

    UniGene: Hs.5302



主站蜘蛛池模板: 无码h肉在线观看免费一区| 国产精品一线二线三线| 丰满岳乱妇一区二区三区| 成 人 黄 色 大片| 好紧好爽好深再快点av在线| 狠狠综合久久综合88亚洲| 少妇高潮惨叫久久久久久| 久久亚洲人成综合网| 亚洲综合网站精品一区二区| 久久久久免费看黄a片app| 国产97色在线 | 免| 久久婷婷五月综合色首页| 香蕉eeww99国产精选免费| 欧美超级乱婬视频播放| 亚洲精品日韩一区二区电影| 午夜福利电影网站鲁片大全| 国产成av人片在线观看无码| 免费国偷自产拍精品视频| 国产特级毛片aaaaaa| 99精品产国品一二三产区| 亚洲国产成人精品无码区在线 | 中文天堂最新版在线www | 亚洲成av人片不卡无码久久 | 被拉到野外强要好爽黑人| 男女做爰真人视频直播| 久久婷婷色香五月综合缴缴情| 国产美女视频免费观看网址| 青青草原精品99久久精品66| 国产成人av大片大片在线播放| 少妇做爰又色又紧夜视频| 午夜亚洲国产理论片二级港台二级| 女女互磨互喷水高潮les呻吟| 超碰香蕉人人网99精品| 麻豆国产原创视频在线播放| 免费裸体无遮挡黄网站免费看| 国产无遮挡无码视频免费软件| 中文字幕人妻被公上司喝醉| 可以免费观看的av毛片下载| 亚洲精品喷潮一区二区三区 | 国产在线拍揄自揄拍无码视频| 国产精品v欧美精品∨日韩|