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  4. LEMD1 Antibody

LEMD1 Antibody

  • 中文名稱：
    LEMD1兔多克隆抗體
  • 貨號：
    CSB-PA715035LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA715035LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA715035LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LEMD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LEMD1
  • 別名：
    LEMD1; LEM domain-containing protein 1; Cancer/testis antigen 50; CT50; LEM domain protein 1; LEMP-1
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LEM domain-containing protein 1 protein (44-151AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，LEMD1 Antibody (CSB-PA715035LA01HU)，的標記方式是Non-conjugated。對于LEMD1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA715035LB01HU LEMD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA715035LC01HU LEMD1 Antibody, FITC conjugated
    Biotin CSB-PA715035LD01HU LEMD1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Data show that LEM domain containing 1 (LEMD1)has five transcript splicing variants (variant 1 [V1] - variant 5 [V5]), and that LEMD1 V1, V2 and V3 is expressed in testis and CR-CSCs/CICs, whereas LEMD1 V4 and V5 is ubiquitously expressed. PMID: 28219643
    2. Downregulation of LEMD1 expression inhibited adhesion and transmigration of OSCCs. PMID: 27280633
    3. Of the prostate cancer samples, 10, 10, 23 and 40% showed ODF1, ODF2, LEMD1 and SPATA19 specific bands, respectively, but none of the BPH samples expressed any of these genes. PMID: 20682177
    4. LEM domain-containing 1 is a novel testis-specific gene expressed in colorectal cancers PMID: 15254688
  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 組織特異性：
    Testis-specific. Isoform 6 is detected in 17 of 18 colon cancer tissues examined.
  • 數據庫鏈接：

    HGNC: 18725

    OMIM: 610480

    KEGG: hsa:93273

    STRING: 9606.ENSP00000356121

    UniGene: Hs.655520



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