在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LECT2 Antibody

  • 中文名稱:
    LECT2兔多克隆抗體
  • 貨號(hào):
    CSB-PA012855LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA012855LA01HU diluted at 1:400 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) LECT2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    chm II antibody; chm2 antibody; Chondromodulin II antibody; hLECT2 antibody; LECT 2 antibody; LECT-2 antibody; LECT2 antibody; LECT2_HUMAN antibody; Leukocyte cell derived chemotaxin 2 antibody; Leukocyte cell-derived chemotaxin-2 antibody; MGC126628 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Leukocyte cell-derived chemotaxin-2 protein (24-151AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,LECT2 Antibody (CSB-PA012855LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于LECT2 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA012855LB01HU LECT2 Antibody, HRP conjugated ELISA
    FITC CSB-PA012855LC01HU LECT2 Antibody, FITC conjugated
    Biotin CSB-PA012855LD01HU LECT2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. Does not show metalloendopeptidase activity.
  • 基因功能參考文獻(xiàn):
    1. Overexpression of LECT2 or treatment with a recombinant LECT2 protein impaired the colony-forming ability and motility of non-small cell lung cancer cells harboring high levels of activated EGFR and MET. PMID: 30453282
    2. Circulating LECT2 concentrations were increased in individuals with NAFLD and those with MetS, but not in those with atherosclerosis. The relationship between LECT2 and both NAFLD and MetS might be mediated by its association with abdominal obesity and lipid metabolism. PMID: 28376109
    3. VFA was the strongest predictor of plasma LECT2 that is a potential biomarker linking visceral obesity to dyslipidemia PMID: 28278265
    4. LECT2 was found to be catalytically inactive as a metalloendopeptidase against various types of peptide sequences, including pentaglycine. PMID: 27334921
    5. the tissue levels of THBS2 and LECT-2 may correlate with the stage of atherosclerosis. PMID: 28039493
    6. findings indicated that serum LECT2 level is negatively associated with the presence of diabetic retinopathy and suggest that low circulating LECT2 level is a risk factor for diabetic retinopathy PMID: 27816666
    7. LECT2 amyloidosis is prevalent among Hispanic decedents in New Mexico. PMID: 26912093
    8. ALECT2, which was initially thought to affect mainly Hispanics in the United States, appears to represent an important and likely underrecognized etiology of chronic kidney disease among Egyptians and probably in other ethnic groups around the world PMID: 26867784
    9. Localized LECT2 amyloidosis of the adrenal gland with coexisting MGUS: a diagnostic challenge. PMID: 26048244
    10. LECT2 immunostain is useful in confirming subtype of amyloid within the liver in ALECT2.. PMID: 25602789
    11. Amyloidosis derived from leukocyte chemotactic factor 2 (ALECT2) is a recently described disease. Here, we report the characteristics and outcome of 72 patients with renal ALECT2, which included 19 who had another kidney disease on biopsy. PMID: 24451324
    12. There were no mutations detected in the LECT2 gene, although all renal leukocyte chemotactic factor 2 amyloidosis patients tested were homozygous for the G nucleotide in a non-synonymous SNP at position 172. PMID: 24522497
    13. LECT2 is regulated by beta-catenin in HCC in both mice and men, but serum LECT2 reflects beta-catenin activity only in mice. Serum LECT2 could be a potential biomarker of HCC in patients. PMID: 24892551
    14. First Nations people from British Columbia who presented with chronic kidney disease, were found to be due to LECT2 amyloidosis. PMID: 25064673
    15. The study indicates that serum LECT2 levels are increased by obesity and fatty liver, and suggests that LECT2 is a novel obesity-related protein. PMID: 24390366
    16. The data from this study show that weak LECT2 staining should be regarded as indeterminate or a negative result and does not per se allow diagnosis of specific amyloid type. The diagnosis of LECT2 renal amyloidosis may require LMD/MS confirmation. PMID: 24792621
    17. These results demonstrate the involvement of LECT2 in glucose metabolism and suggest that LECT2 may be a therapeutic target for obesity-associated insulin resistance. PMID: 24478397
    18. ALect2 is a common cause of hepatic amyloidosis in the population of the United States, and subtyping hepatic amyloid deposits by an accurate analytic method such as MS is required for optimal clinical management of hepatic amyloidosis patients PMID: 24415538
    19. These findings reveal a novel, specific inhibitory function of LECT2 in hepatocellular carcinoma by the direct binding and inactivation of MET. PMID: 24114941
    20. preliminary X-ray analysis of human leukocyte cell-derived chemotaxin 2 (LECT2). PMID: 23519812
    21. Re-expression of LECT2 significantly reduced the migration and invasion of human hepatocellular carcinoma cells in vitro and significantly reduced their growth in vivo. PMID: 21394108
    22. LECT2-associated renal amyloidosis represents a unique and perhaps not uncommon disease, especially in Mexican Americans. PMID: 20951486
    23. LECT2, which encodes a protein with chemotactic properties for human neutrophils, is a direct target gene of Wnt/beta-catenin signaling in the liver. PMID: 15239100
    24. LECT2 participates in liver regeneration and injury following hepatectomy. PMID: 15561248
    25. Serum LECT2 levels may be a prognostic indicator of recovery from liver failure. PMID: 15561249

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Secreted.
  • 蛋白家族:
    LECT2/MIM-1 family
  • 組織特異性:
    Highly expressed in adult and fetal liver and weakly in testis. Not expressed in bone marrow.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 6550

    OMIM: 602882

    KEGG: hsa:3950

    STRING: 9606.ENSP00000274507

    UniGene: Hs.512580



主站蜘蛛池模板: 久章草国语自产拍在线观看| 久久伊人蜜桃av一区二区| 一本加勒比hezyo无码资源网| 日本熟妇色xxxxxhd| 国产亚洲精选美女久久久久| 东北妇女xx做爰视频| 久久久久国产精品嫩草影院 | 无码少妇一区二区性色av| 国产成人无码免费看片软件| 国产成人无码av在线影院| 先锋影音人妻啪啪va资源网站| 成人午夜福利视频| 国产精品久久久久野外| 亚洲性视频免费视频网站| 亚洲日韩一中文字暮av| 精品人妻系列无码一区二区三区| 日韩人妻熟女中文字幕a美景之屋| 国产美女嘘嘘嘘嘘嘘| 伊人精品无码av一区二区三区| 中文字幕亚洲情99在线| 欧美大肥婆大肥bbbbb| 在教室伦流澡到高潮hgl动漫| 久久久久久久综合日本| 国产免费久久精品99久久| 1000部又爽又黄无遮挡的视频| 中文字幕免费无码专区| 青青草原综合久久大伊人精品| 亚洲色欲久久久久综合网| 国产女人高潮抽搐叫床视频| 欧美成人精品一区二区三区色欲| 无码国产69精品久久久久孕妇| 国产日韩欧美亚洲精品中字| 国产成人午夜无码电影在线观看| 成人无码精品1区2区3区免费看| 丰满饥渴老女人hd| 日韩精品一区二区大桥未久| 久久久99久久久国产自输拍| 我的公把我弄高潮了视频| 久久亚洲道色综合久久| 一区二区三区无码免费看| 日日躁夜夜躁狠狠躁超碰97|