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  4. LANCL1 Antibody, FITC conjugated

LANCL1 Antibody, FITC conjugated

  • 中文名稱：
    LANCL1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA012742LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LANCL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LANCL1
  • 別名：
    40 kDa erythrocyte membrane protein antibody; G protein-coupled receptor 69A antibody; GPR69A antibody; LanC (bacterial lantibiotic synthetase component C) like 1 antibody; LanC lantibiotic synthetase component C like 1 (bacterial) antibody; LanC-like protein 1 antibody; LANC1_HUMAN antibody; LANCL1 antibody; p40 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LanC-like protein 1 protein (50-150AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during normal postnatal development and in response to oxidative stresses probably through GSH antioxidant defense mechanism. May play a role in EPS8 signaling. Binds glutathione.
  • 基因功能參考文獻：
    1. Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense. PMID: 22891245
    2. the crystal structures of human LanCL1, both free of and complexed with glutathione, revealing glutathione binding to a zinc ion at the putative active site formed by conserved GxxG motifs PMID: 19528316
  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    LanC-like protein family
  • 組織特異性：
    Detected in erythrocytes, brain, kidney, testis, ovary, heart, lung, placenta and spleen (at protein level). Ubiquitous. Strongly expressed in brain, spinal cord, pituitary gland, kidney, heart, skeletal muscle, pancreas, ovary and testis.
  • 數據庫鏈接：

    HGNC: 6508

    OMIM: 604155

    KEGG: hsa:10314

    STRING: 9606.ENSP00000233714

    UniGene: Hs.13351



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