在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LAMTOR3 Antibody

LAMTOR3 Antibody

  • 中文名稱：
    LAMTOR3兔多克隆抗體
  • 貨號：
    CSB-PA013477GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    LAMTOR3 antibody; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 antibody; LTOR3_HUMAN antibody; MAP2K1IP1 antibody; MEK binding partner 1 antibody; MEK partner 1 antibody; MEK-binding partner 1 antibody; Mitogen activated protein kinase kinase 1 interacting protein 1 antibody; Mitogen-activated protein kinase kinase 1-interacting protein 1 antibody; Mitogen-activated protein kinase scaffold protein 1 antibody; Mp1 antibody; Ragulator complex protein LAMTOR3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MAPKSP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
  • 基因功能參考文獻：
    1. Studied role of MEK partner-1 (LAMTOR3) in driving MEK/ERK pathway in EGFRviii-expressing glioma cells. PMID: 28830458
    2. BCL2 expression in mesennchymal lung cancer cells was induced by ERK1 activity through the upregulation of the MEK1/ERK1 scaffold protein MEK partner-1. Interfering with the MEK1/MP1/ERK1 axis using a MEK1 inhibitor or MP1 depletion repressed BCL2 expression and sensitized MLCCs to chemoradiotherapy. PMID: 28606806
    3. The present study was aimed at investigating whether the miR-29c binding site single nucleotide polymorphisms within the 3'-UTRs of LAMTOR3 gene affected the gastric cancer risk. PMID: 25661340
    4. we demonstrate that the MAPK scaffold protein MEK partner 1 (MP1) is important for gastrin-induced phosphorylation of ERK1 and ERK2 and that MP1 promotes gastrin-induced proliferation of AGS-GR cells PMID: 23408059
    5. identified polymorphisms in LAMTOR2 and LAMTOR3 do not seem to play a relevant role in breast cancer PMID: 23341997
    6. A complex encoded by the MAPKSP1, ROBLD3, and c11orf59 genes interacts with the Rag GTPases, recruits them to lysosomes, and is essential for mTORC1 activation PMID: 20381137
    7. We investigated the neuroprotective effect of glial-derived neurotrophic factor (GDNF) upon alcohol-exposed B92 cultures, as well as the role of the cytoskeleton and mitogen-activated protein kinase (MAPK) pathways in this effect. PMID: 17113937

    顯示更多

    收起更多

  • 亞細胞定位：
    Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族：
    LAMTOR3 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15606

    OMIM: 603296

    KEGG: hsa:8649

    STRING: 9606.ENSP00000424183

    UniGene: Hs.433332



主站蜘蛛池模板： 人人妻人人澡人人爽人人dvd| 玩两个丰满老熟女久久网| 无码成a毛片免费| 无码一区二区三区| 国产成人啪精品视频免费网站软件| 免费人成又黄又爽的视频| 国产成人无码午夜视频在线播放 | 久久电影网午夜鲁丝片免费| 久久精品无码一区二区无码| 冲田杏梨av一区二区三区| 欧美日本特级婬片视频| 欧美午夜精品久久久久免费视| 久久国语露脸国产精品电影| 人妻精品国产一区二区| 国产97人人超碰caoprom| 女人摸下面自熨视频在线播放| 国产精品亚洲а∨无码播放麻豆 | 少妇高潮喷潮久久久影院| 亚洲最大av一区二区三区| av人摸人人人澡人人超碰手机版| 精品欧美一区二区在线观看| 欧美日韩国产精品自在自线| 国产综合有码无码视频在线 | 五月丁香六月激情综合在线视频| 真人一进一出120秒试看| 亚洲国产av一区二区三区四区| 黑人大战亚洲人精品一区| 四虎影视88aa久久人妻| 亚洲中文精品久久久久久| 永久免费无码av网站在线观看| 国产精品永久免费| 97久章草在线视频播放| 又色又爽又黄的视频国内| 国产无套中出学生姝| 永久免费精品精品永久-夜色| 亚洲国产av无码综合原创国产 | 免费视频国产在线观看| 噜噜久久噜噜久久鬼88| 永久免费的av在线电影网无码| 久久无码潮喷a片无码高潮| 国产成人精选在线观看不卡|