在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LAMB1 Antibody

  • 中文名稱:
    LAMB1兔多克隆抗體
  • 貨號(hào):
    CSB-PA012730LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA012730LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) LAMB1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    CLM antibody; Cutis laxa with marfanoid phenotype antibody; LAM B1 antibody; LAMB 1 antibody; LAMB1 antibody; LAMB1_HUMAN antibody; Laminin B1 antibody; Laminin B1 chain antibody; Laminin beta 1 chain antibody; Laminin beta 1 chain precursor antibody; Laminin beta1 antibody; Laminin subunit beta 1 antibody; Laminin subunit beta-1 antibody; Laminin-1 subunit beta antibody; Laminin-10 subunit beta antibody; Laminin-12 subunit beta antibody; Laminin-2 subunit beta antibody; Laminin-6 subunit beta antibody; Laminin-8 subunit beta antibody; LIS5 antibody; MGC142015 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Laminin subunit beta-1 protein (523-661AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,LAMB1 Antibody (CSB-PA012730LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于LAMB1 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA012730LB01HU LAMB1 Antibody, HRP conjugated ELISA
    FITC CSB-PA012730LC01HU LAMB1 Antibody, FITC conjugated
    Biotin CSB-PA012730LD01HU LAMB1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
  • 基因功能參考文獻(xiàn):
    1. High cytoplasmic laminin expression is associated with Oral Squamous Cell Carcinomas. PMID: 29479990
    2. Treatment of Neuroscreen-1 (NS-1) cells with laminin-1 or YIGSR peptide, which corresponds to a sequence in laminin-1 beta1 chain that binds to 67LR, induced a decrease in the cell-surface expression of 67LR and caused its internalization. PMID: 29108990
    3. In vitro activation of PDGFR-alpha leads to translational activation of LAMB1, which in turn induces an invasive and metastatic phenotype of hepatocellular carcinoma cells exhibiting K19 expression. PMID: 28783171
    4. LAMB1 may affect the initiation and progression of pneumoconiosis, or serve as a potential biomarker of pneumoconiosis for diagnosis and genetic susceptibility. PMID: 28444932
    5. LAMB1 is a potential serological biomarker that could be used in conjunction with carcinoembryonic antigen for diagnosis of colorectal cancer. PMID: 26359947
    6. These results suggest that MUC5B production can be regulated by ECM components and that MUC5B is upregulated by fibronectin and laminin via the integrin, ERK, and NF-kappaB dependent pathway. PMID: 26057585
    7. An association was found between LAMB1 rs2158836 polymorphisms and symptom severity in Korean autism spectrum disorder patients. PMID: 25774865
    8. LAMB1 single nucleotide polymorphism rs886774 was associated with early onset Ulcerative colitis and, thus, suggests a fundamentally different mechanism of early disease pathogenesis in Ulcerative colitis versus Crohn's disease. PMID: 25664710
    9. Upregulation of LAMB1 expression was highly correlated with the downregulation of miR-124-5p. LAMB1 protein expression was suppressed by miR-124-5p. PMID: 24497408
    10. The phenotype due to LAMB2 mutations appears to be similar between different ethnic groups. PMID: 23679161
    11. Homozygous deleterious mutations in LAMB1. PMID: 23472759
    12. Laminin beta1 and integrin alpha2 expression is elevated in the anterior temporal neocortex tissue from patients with intractable epilepsy. PMID: 21370991
    13. We did not find an association of rs6949033 (LAMB1) with ulcerative colitis. PMID: 21744425
    14. mRNA encoding laminin-alpha1, -beta1, and -gamma1 chains was expressed in 90% of endometriotic lesions. PMID: 12615822
    15. alteration of LAMB1 expression is associated with the genesis and development of uterine leiomyoma PMID: 15706419
    16. laminin beta1 chain (a constituent of laminin-8) was typically found in vessel walls of carcinomas and their metastases but not in those of normal breast PMID: 15987446
    17. laminin supports platelet adhesion depending on the interaction of VWF and GPIb-IX-V under pathophysiological high shear flow PMID: 18450753
    18. Meningiomas increase in size through increased production of extracellular matrix; furthermore, the proliferation of cells typically associated with neoplasia requires considerable interaction with the extracellular matrix. PMID: 18474427
    19. Elevated expression of laminin beta1 mRNA and protein in the hippocampus suggests that laminin beta1 may play a role in the development of epileptic seizures in patients with intractable epilepsy. PMID: 18691630
    20. beta2 chain-containing laminins (beta2-laminins) bound more avidly to alpha3beta1 and alpha7X2beta1 integrins than beta1 chain-containing laminins (beta1-laminins). PMID: 19147489
    21. The presence of nuclear beta-catenin and high content of mmp-9 in the tumor were associated with abnormal accumulation of laminin in the cytoplasm. These changes were characteristic of colorectal cancer with high invasive metastatic potential. PMID: 19526105
    22. LAMB1 new susceptibility loci for ulcerative colitis PMID: 19915572

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Lissencephaly 5 (LIS5)
  • 亞細(xì)胞定位:
    Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6486

    OMIM: 150240

    KEGG: hsa:3912

    STRING: 9606.ENSP00000222399

    UniGene: Hs.650585



主站蜘蛛池模板: 无码无套少妇18p在线直播| 精品久久久久久无码中文野结衣| 免费视频欧美无人区码| 天美传媒一区二区| 国产精品日韩av在线播放| 综合激情丁香久久狠狠| 久久精品国产国产精品四凭| 亚洲线精品一区二区三区| 中出人妻中文字幕无码| 日本三级成本人网站| 国产精品狼人久久久久影院| 无码人妻一区二区中文| 玩弄少妇人妻中文字幕| 久久久久久综合网天天| 亚洲熟妇无码av另类vr影视| 欧美精品a∨在线观看| 欧美乱强伦xxxx孕妇| 漂亮人妻被中出中文字幕| 女人高潮被爽到呻吟在线观看| 中文韩国午夜理伦三级好看| 天天影视网天天综合色| 国产成人18黄网站| 欧美亚洲综合在线一区| 中国熟妇牲交视频| 99r在线精品视频在线播放| 日本高清熟妇老熟妇| 99re热这里只有精品视频| 性xxxx18免费观看视频| 免费午夜福利不卡片在线播放| 侵犯强奷高清无码| 欧洲亚洲色一区二区色99| 久久av高潮av无码av| 成人美女黄网站色大色费全看| 久99久热只有精品国产女同| 尤物yw193无码点击进入| 色综合久久中文综合网| 日本熟妇浓毛hdsex| 久久亚洲精品无码va白人极品 | 国产精品186在线观看在线播放| 中文国产成人精品久久不卡 | 免费网站观看www在线观看|