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  4. LACTB2 Antibody

LACTB2 Antibody

  • 中文名稱：
    LACTB2兔多克隆抗體
  • 貨號：
    CSB-PA706635LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA706635LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA706635LA01HU at dilution of 1:100
    • Immunofluorescent analysis of HepG2 cells using CSB-PA706635LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) LACTB2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LACTB2
  • 別名：
    Beta lactamase like protein 2 antibody; Beta-lactamase-like protein 2 antibody; CGI 83 antibody; CGI-83 antibody; LACB2_HUMAN antibody; Lactamase beta 2 antibody; LACTB2 antibody; MGC112672 antibody; MGC140671 antibody; MGC7674 antibody; OTTHUMP00000226691 antibody; OTTHUMP00000226692 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Endoribonuclease LACTB2 protein (6-288AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，LACTB2 Antibody (CSB-PA706635LA01HU)，的標記方式是Non-conjugated。對于LACTB2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA706635LB01HU LACTB2 Antibody, HRP conjugated ELISA
    FITC CSB-PA706635LC01HU LACTB2 Antibody, FITC conjugated
    Biotin CSB-PA706635LD01HU LACTB2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
  • 基因功能參考文獻：
    1. This genome-wide study of never smokers from the general population identified two independent regions related to erythrocyte cadmium. The strongest locus covers the XKR9 and LACTB2 genes, which both could have related functions in cadmium absorption and metabolism PMID: 27005419
    2. this study discovered that LACTB2 is an endoribonuclease that is involved in the turnover of mitochondrial RNA, and is essential for mitochondrial function in human cells. PMID: 26826708
    3. Disruption of NCOA2 by recurrent fusion with LACTB2 in colorectal cancer PMID: 25823027
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Metallo-beta-lactamase superfamily, Glyoxalase II family
  • 數據庫鏈接：

    HGNC: 18512

    KEGG: hsa:51110

    STRING: 9606.ENSP00000276590

    UniGene: Hs.118554



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