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  4. L1 Antibody
  • 中文名稱：
    L1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA08359A0Rb
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：

    The rabbit anti-human papillomavirus type 18 L1 polyclonal antibody was developed in the rabbit using the recombinant HPV18 major capsid protein L1 protein (1-568aa) as the immunogen. After immunization, the rabbit anti-serum was collected and then purified via protein G affinity chromatograph to obtain the high purity HPV18 L1 polyclonal antibody. Its purity is above 95%.

    This HPV18 L1 polyclonal antibody can detect the HPV18 major capsid protein L1. And it has been quality validated for ELISA. It may help to study the roles of the HPV18 major capsid protein L1 in the HPV18 infection-associated research.

  • 產(chǎn)品名稱：
    Rabbit anti-Human papillomavirus type 18 L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    L1
  • 別名：
    L1 antibody; Major capsid protein L1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human papillomavirus type 18
  • 免疫原：
    Recombinant HPV18 Major capsid protein L1 protein (1-568AA)
  • 免疫原種屬：
    Human papillomavirus type 18
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，L1 Antibody (CSB-PA08359A0Rb)，的標(biāo)記方式是Non-conjugated。對(duì)于L1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA08359B0Rb L1 Antibody, HRP conjugated ELISA
    FITC CSB-PA08359C0Rb L1 Antibody, FITC conjugated
    Biotin CSB-PA08359D0Rb L1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
  • 基因功能參考文獻(xiàn)：
    1. L1 sequences were strongly methylated in all cervical carcinomas studied; hypothesize that L1 is preferentially methylated after integration of the HPV genome into the cellular DNA PMID: 16472835
  • 亞細(xì)胞定位：
    Virion. Host nucleus.
  • 蛋白家族：
    Papillomaviridae L1 protein family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: vg:1489090



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