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L Antibody

Rare Species
  • 中文名稱:
    L兔多克隆抗體
  • 貨號:
    CSB-PA806333LA01VBE
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: L antibody at 7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 28 kDa
      Observed band size: 28 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Vesicular stomatitis Indiana virus L Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    L
  • 別名:
    L antibody; RNA-directed RNA polymerase L antibody; Protein L antibody; Large structural protein antibody; Replicase antibody; Transcriptase) [Includes: RNA-directed RNA polymerase antibody; EC 2.7.7.48); mRNA antibody; guanine-N(7)-)-methyltransferase antibody; EC 2.1.1.56); GDP polyribonucleotidyltransferase antibody; EC 2.7.7.88); Cap-specific mRNA antibody; nucleoside-2'-O-)-methyltransferase 2 antibody; EC 2.1.1.296)] antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Vesicular stomatitis Indiana virus
  • 免疫原:
    Recombinant Vesicular stomatitis Indiana virus RNA-directed RNA polymerase L protein (598-784AA)
  • 免疫原種屬:
    Vesicular stomatitis Indiana virus
  • 標記方式:
    Non-conjugated

    本頁面中的產品,L Antibody (CSB-PA806333LA01VBE),的標記方式是Non-conjugated。對于L Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA806333LB01VBE L Antibody, HRP conjugated ELISA
    FITC CSB-PA806333LC01VBE L Antibody, FITC conjugated
    Biotin CSB-PA806333LD01VBE L Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Responsible for RNA synthesis (replicase and transcriptase), cap addition, and cap methylation. Performs also the polyadenylation of subgenomic mRNAs by a stuttering mechanism at a slipery stop site present at the end of viral genes. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, thereby initiating either genome replication or mRNA transcription. In the transcription mode, the polymerase performs the sequential transcription of all mRNAs using a termination-reinitiation mechanism responding to gene start and gene end signals. Some polymerase disengage from the template at each gene junction, resulting in a decreasing abundance of transcripts from the 3' to the 5' end of the genome. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein helps the polymerase to engage the N-RNA template and acts as processivity factor. Polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. In the replication mode, the polymerase replicates the whole viral genome without recognizing the gene end transcriptional signals. The ability of the polymerase to override the gene end signals as it is producing the antigenome is probably due to replicative RNA becoming encapsidated with nucleoprotein as it is synthesized.
  • 亞細胞定位:
    Virion. Host cytoplasm.
  • 蛋白家族:
    Rhabdoviridae protein L family


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