在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KRT13 Antibody

  • 中文名稱:
    KRT13兔多克隆抗體
  • 貨號:
    CSB-PA297945
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA297945(KRT13 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA297945(KRT13 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human esophagus cancer tissue, Primary antibody: CSB-PA297945(KRT13 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    47 kDa cytokeratin antibody; CK-13 antibody; CK13 antibody; Cytokeratin 13 antibody; Cytokeratin-13 antibody; K13 antibody; K1C13_HUMAN antibody; Ka13 antibody; Keratin 13 antibody; Keratin antibody; keratin type I cytoskeletal 13 antibody; Keratin-13 antibody; Krt-1.13 antibody; Krt1-13 antibody; KRT13 antibody; MGC161462 antibody; MGC3781 antibody; type I cytoskeletal 13 antibody; Type I keratin Ka13 antibody; WSN2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human KRT13
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:200-1:1000
    IHC 1:5-1:20
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Oral white sponge nevus may manifest variable clinical features. The novel mutation found in the KRT13 gene is believed to add evidence for a mutational hotspot in the mucosal keratins PMID: 29476668
    2. this study reports that KRT13 plays a directive role in prostate cancer bone, brain, and soft tissue metastases PMID: 27835867
    3. Keratin 13 gene is epigenetically suppressed during TGFB1-induced epithelial-mesenchymal transition in a human keratinocyte cell line. PMID: 29326042
    4. Four rare missense variants were identified (ACTBL2 rs73757391 (5q11.2), BTD rs200337373 (3p25.1), KRT13 rs150321809 (17q21.2) and MC2R rs104894658 (18p11.21)), but only MC2R rs104894668 had a large effect size (OR = 9.66). PMID: 27378695
    5. KRT13 expression is associated with poor prognosis at multiple stages of disease progression PMID: 27711225
    6. Loss of CK13 expression is associated with invasive oral squamous cell carcinoma. PMID: 26225699
    7. Low KRT13 mRNA expression is associated with oral squamous cell carcinoma. PMID: 25735388
    8. Decreased KRT13 was associated with Esophageal Squamous Cell Carcinoma. PMID: 25851906
    9. Our data provide mechanistic insights into the epigenetic silencing of KRT13 genes in OSCC cells and might be useful for the development of diagnostic markers and novel therapeutic approaches against OSCCs. PMID: 25527207
    10. keratin14 expression can be used to detect early epithelial dysplasia, and that keratin13 and keratin17 expression are useful for detecting neoplastic changes PMID: 24471966
    11. Immunoexpression of CK13 and CK17 in light green-stained superficial cells was associated with more severe morphological atypia in tongue squamous cell carcinoma PMID: 24247036
    12. Fluorescent keratin 13 integrates into the endogenous keratin cytoskeleton in human vulva carcinoma-derived A431 cells, thereby serving as a reliable marker of keratin dynamics. PMID: 23757496
    13. Loss of K13 in oral carcinoma in situ is partly due to its gene repression, but may also be due to some unknown post-translational events. PMID: 22301701
    14. Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19. PMID: 21738394
    15. CK13 expression is elevated in KB cells treated with all-trans retinoic acid or arsenic trioxide. PMID: 19489262
    16. exhibits a regular expression pattern in luminal epithelial cells of secretory phase human endometrium PMID: 11906920
    17. Metaplastic squamous cells differentiate with a decrease of CK18 and an increase of CK13 expression. PMID: 16836912
    18. CK13 positive staining occurs in cervical squamous tumors and in mucinous cervical type adenocarcinomas, while there was no positive staining in non-neoplastic cervical glandular elements PMID: 16949723
    19. The different ligand regulations of KRT13 are due to ligand-differential recruitment of ER and coactivators. PMID: 18951949

    顯示更多

    收起更多

  • 相關疾?。?/div>
    White sponge nevus 2 (WSN2)
  • 蛋白家族:
    Intermediate filament family
  • 組織特異性:
    Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
  • 數據庫鏈接:

    HGNC: 6415

    OMIM: 148065

    KEGG: hsa:3860

    STRING: 9606.ENSP00000246635

    UniGene: Hs.654550



主站蜘蛛池模板: 久久不见久久见免费影院视频| 国产av国片精品一区二区| 人人妻人人澡人人爽偷拍台湾| 18禁止观看强奷免费国产大片| 一本无码中文字幕在线观| 国产偷国产偷亚州清高app | 欧美牲交a欧美牲交aⅴ免费真| 日韩国产成人无码av毛片| 欧美顶级metart裸体全部自慰| 亚洲国产综合无码一区| 一区三区不卡高清影视| 真实国产乱子伦在线视频| www婷婷av久久久影片| 性色av蜜臀av色欲av| 国产精品卡一卡二卡三| 99re久久资源最新地址| 国产av成人无码精品网站| 精品国产一区二区三区四区| 久久亚洲春色中文字幕久久久| 88国产精品欧美一区二区三区| 麻豆国产va免费精品高清在线| 精品无码欧美黑人又粗又| 亚洲性色成人av| 亚洲中文字幕aⅴ天堂| 欧美牲交a欧美牲交aⅴ久久| 久久天天躁狠狠躁夜夜av| 亚洲综合另类小说色区| 大伊香蕉精品一区二区| 人妻巨大乳hd免费看| 无码人妻丰满熟妇啪啪网站| 国精产品999一区二区三区有限| 日日天日日夜日日摸| 一边啪啪一边呻吟av夜夜嗨 | 色综合天天综合网中文| 男人的天堂av社区在线| 狠狠色噜噜狠狠狠777米奇888| 国产日韩一区二区三区在线观看| 国产乱女乱子视频在线播放| 国产精品十八禁在线观看| 国产午夜大地久久| 成在人线av无码免费看网站|