在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLK8 Antibody

  • 中文名稱:
    KLK8兔多克隆抗體
  • 貨號(hào):
    CSB-PA012459GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    KLK8
  • 別名:
    Brain serine protease 1 antibody; BSP1 antibody; hK8 antibody; HNP antibody; HPN antibody; Kallikrein 8 (neuropsin/ovasin) antibody; Kallikrein related peptidase 8 antibody; Kallikrein-8 antibody; Kallikrein8 antibody; KLK 8 antibody; Klk8 antibody; KLK8 protein type 1 antibody; KLK8 protein type 2 antibody; KLK8_HUMAN antibody; Neuropsin antibody; neuropsin type 1 antibody; Neuropsin type 1; included antibody; Neuropsin type 2 antibody; Neuropsin type 2; included antibody; Neuropsin; mouse; homolog of antibody; NP antibody; NRPN antibody; Ovasin antibody; PRO322 antibody; Protease serine 19 antibody; PRSS 19 antibody; PRSS19 antibody; Serine protease 19 antibody; Serine protease kallikrein antibody; Serine protease kallikrein/ovasin/neuropsin antibody; Serine protease TADG 14 antibody; Serine protease TADG-14 antibody; Serine protease TADG14 antibody; TADG 14 antibody; TADG14 antibody; Tumor associated differentially expressed gene 14 antibody; Tumor associated differentially expressed gene 14 protein antibody; Tumor-associated differentially expressed gene 14 protein antibody; UNQ283 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human KLK8
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
  • 基因功能參考文獻(xiàn):
    1. Telbivudine treatment resulted in increased levels of serum KLK8 protein. Furthermore, eGFR increase was associated with body height-adjusted, post-treatment KLK8 levels PMID: 29936485
    2. mRNA expression levels of KLK6 and KLK8 in advanced serous ovarian cancer PMID: 27483364
    3. elevated KLK8 expression was correlated with the progression of colorectal cancer. PMID: 28142115
    4. KLK8 mRNA expression is associated with aggressive tumor characteristics and it can serve as a novel independent biomarker of unfavorable prognosis for BC patients. PMID: 26099606
    5. Occurring independently of cyclophilins and of furin that mediate human papillomavirus 16 L2 exposure, KLK8-mediated cleavage of L1 likely facilitated access to L2, located in the capsid lumen, and potentially uncoating. PMID: 25926655
    6. It dissects a schizophrenic susceptibility gene, NRG1. PMID: 24614639
    7. KLK8 and KLK14 can signal differentially via the PARs to affect tissue function PMID: 22505524
    8. KLK8 as a new active serine protease in human stratum corneum and sweat PMID: 20940292
    9. The results of this study indicate that most salivary gland tumors show high levels of expression of KLK8. PMID: 20614312
    10. The KLK8-T4 alternative splice variant, alone or in combination, may be a new independent marker of unfavorable prognosis in lung cancer. PMID: 20360129
    11. Cervical cancer expressed high level of TADG-14. May play important role in invasion and metastasis. Appears only in abundance in tumor tissue and contains secretion signal sequence. Possible diagnostic use or as therapeutic target. PMID: 14749636
    12. Expression of hK8 is increased during the development of ovarian cancer and down-regulated during ovarian cancer progression. PMID: 15138549
    13. Amino-terminal sequencing of the activated enzyme demonstrated the cleavage of a 9-aa propeptide from the pro-enzyme; substrate specificiy and effect of metal ions and pH is demonstrated PMID: 16800733
    14. KLK8 expression confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness. PMID: 17178872
    15. analysis of how a mutation leads to the origin of a novel splice form of neuropsin (KLK8), a gene involved in learning and memory PMID: 17487847
    16. kallikreins 5, 7, 8, and 10 are abundantly expressed in human OSCC and may be implicated in malignant progression PMID: 19085836
    17. The processed end-point enzymes are the same for both type I and type II kallikrein 8, suggesting that the emergence of type II kallikrein 8 in the human brain likely leads to functional modifications of kallikrein 8. PMID: 19125171
    18. Combination of KLK2, 3, 13, and 14 and KLK1, 2, 5, 6, 7, 8, 10, 13, and 14 showed very strong discriminatory potential for semen liquefaction and viscosity, respectively. PMID: 19558318

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted. Cytoplasm. Note=Shows a cytoplasmic distribution in the keratinocytes.
  • 蛋白家族:
    Peptidase S1 family, Kallikrein subfamily
  • 組織特異性:
    Isoform 1 is predominantly expressed in the pancreas. Isoform 2 is expressed in adult brain and hippocampus. Isoform 1 and isoform 2 are found in fetal brain and placenta. Detected in salivary gland, uterus, thymus, breast, testis and kidney but not in sp
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6369

    OMIM: 605644

    KEGG: hsa:11202

    UniGene: Hs.104570



主站蜘蛛池模板: 拍国产乱人伦偷精品视频| 毛片免费视频肛交颜射免费视频| 亚洲2022国产成人精品无码区| 亚洲中文久久精品无码照片| 天堂va欧美ⅴa亚洲va| av鲁丝一区鲁丝二区鲁丝三区| 色噜噜狠狠色综合日日| 国产精品人成视频国模| 男女猛烈无遮挡免费视频app| 欧美午夜精品久久久久免费视 | 人妻少妇精品视频一区二区三区| 中文乱码免费一区二区| 中文字幕亚洲男人的天堂网络| 日韩亚洲欧美中文高清在线| 免费国精产品自偷自偷免费看| 天天爱天天做天天爽夜夜揉| 潮喷大喷水系列无码久久精品| 大陆极品少妇内射aaaaa| 少妇挑战三个黑人惨叫4p国语| 国产欧美另类久久久精品图片| 亚洲日韩中文字幕在线不卡最新| 窝窝午夜色视频国产精品破| 成人网站免费观看| 免费网站看v片在线18禁无码| 丰满少妇被猛烈进入试看| 国产成人久久av免费高潮| 精品无码综合一区二区三区| 亚洲午夜成人精品无码| 无码成人一区二区| 亚洲人成网站观看在线播放 | 99久久久国产精品消防器材| 中文精品久久久久人妻不卡| 伊人色综合久久天天小片| 欧美性video高清精品| 破了亲妺妺的处免费视频国产| 一本加勒比hezyo无码资源网| 伊人精品一本久久综合| 亚洲愉拍自拍另类图片| 亚洲欧洲自拍拍偷午夜色| 精产国品一区二区三产区| 国产精品av一区二区三区不卡蜜|