在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLHL7 Antibody

  • 中文名稱:
    KLHL7兔多克隆抗體
  • 貨號:
    CSB-PA812891ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA812891ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA812891ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) KLHL7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KLHL7
  • 別名:
    KLHL7Kelch-like protein 7 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Kelch-like protein 7 protein (427-586AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
  • 基因功能參考文獻(xiàn):
    1. We have expanded the clinical spectrum of KLHL7 autosomal recessive variants by describing a syndrome with features overlapping CS/CISS1 and BOS. PMID: 29074562
    2. KLHL7 is a novel regulator of the nucleolus associated with TUT1 ubiquitination, and pathogenic KLHL7 mutants may provide valuable information to elucidate a mechanism of retinitis pigmentosa etiology. PMID: 29032201
    3. data further support the pathogenic role of KLHL7 mutations in a CS/CISS1-like phenotype--but they do not explain all their clinical manifestations and highlight the high phenotypic heterogeneity associated with mutations in KLHL7 PMID: 27392078
    4. The phenotypes are similar among patients with 3 types of KLHL7 mutations (c.458C>T, c.449G>A, and c.457G>A). PMID: 22084217
    5. KLHL7 forms a dimer, assembles with Cul3 through its BTB and BACK domains, and exerts E3 activity. PMID: 21828050
    6. Observed in 2 Scandinavian families to date, KLHL7 mutation has recently been associated with autosomal dominant retinitis pigmentosa. PMID: 20547956
    7. The present results indicate that KLHL7 antibodies are associated with various cancers, and in some patients also with neurological disease. Whether KLHL7 antibodies can be used as paraneoplastic markers for PNS remains to be determined. PMID: 16918702
    8. Mutations in a BTB-Kelch protein, KLHL7, cause autosomal-dominant retinitis pigmentosa. PMID: 19520207

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Cold-induced sweating syndrome 3 (CISS3); Retinitis pigmentosa 42 (RP42)
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 組織特異性:
    Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15646

    OMIM: 611119

    KEGG: hsa:55975

    STRING: 9606.ENSP00000343273

    UniGene: Hs.654817



主站蜘蛛池模板: 亚洲一区 日韩精品 中文字幕 | 精品动漫一区二区无遮挡| 99久久久无码国产精品9| 18禁裸男晨勃露j毛免费观看 | 色综合天天综合高清网国产在线| 精品国产免费人成电影在线看| 久热国产精品视频一区二区三区 | 亚洲一区av无码专区在线观看| 精品乱码一区二区三区四区| 98国产精品综合一区二区三区| 午夜天堂av天堂久久久| 无码人妻天天拍夜夜爽| 国产99青草视频在线播放视 | 麻豆果冻传媒2021精品传媒一区下载| 久久综合香蕉国产蜜臀av| 久久久久久a亚洲欧洲av| 学生精品国产在线视频| 青青视频免费观看免费| 国产一码二码三码区别| 日本老熟妇乱| 九九线精品视频在线观看| 三级男人添奶爽爽爽视频 | 国产精品女人呻吟在线观看| 在线观看无码av网址| 国产精品后入内射日本在线观看| 少妇午夜啪爽嗷嗷叫视频| 国产午夜无码片在线观看影视| 精品香蕉99久久久久网站| 国精品无码人妻一区二区三区 | 日韩人妻无码一区二区三区综合部| 久久天天躁狠狠躁夜夜躁2012 | 色婷婷五月综合欧美图片| 超薄肉色丝袜一区二区| 欧洲熟妇色xxxx欧美老妇多毛网站 | 久久婷婷色香五月综合缴缴情| 色香阁综合无码国产在线| 99久久精品国产第一页| 国产精品你懂的在线播放| 久久er99国产精品免费| 中文字幕av一区| 国产69精品久久久久久久|