在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLHL7 Antibody

  • 中文名稱:
    KLHL7兔多克隆抗體
  • 貨號:
    CSB-PA812891ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA812891ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA812891ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) KLHL7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KLHL7
  • 別名:
    KLHL7Kelch-like protein 7 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Kelch-like protein 7 protein (427-586AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
  • 基因功能參考文獻(xiàn):
    1. We have expanded the clinical spectrum of KLHL7 autosomal recessive variants by describing a syndrome with features overlapping CS/CISS1 and BOS. PMID: 29074562
    2. KLHL7 is a novel regulator of the nucleolus associated with TUT1 ubiquitination, and pathogenic KLHL7 mutants may provide valuable information to elucidate a mechanism of retinitis pigmentosa etiology. PMID: 29032201
    3. data further support the pathogenic role of KLHL7 mutations in a CS/CISS1-like phenotype--but they do not explain all their clinical manifestations and highlight the high phenotypic heterogeneity associated with mutations in KLHL7 PMID: 27392078
    4. The phenotypes are similar among patients with 3 types of KLHL7 mutations (c.458C>T, c.449G>A, and c.457G>A). PMID: 22084217
    5. KLHL7 forms a dimer, assembles with Cul3 through its BTB and BACK domains, and exerts E3 activity. PMID: 21828050
    6. Observed in 2 Scandinavian families to date, KLHL7 mutation has recently been associated with autosomal dominant retinitis pigmentosa. PMID: 20547956
    7. The present results indicate that KLHL7 antibodies are associated with various cancers, and in some patients also with neurological disease. Whether KLHL7 antibodies can be used as paraneoplastic markers for PNS remains to be determined. PMID: 16918702
    8. Mutations in a BTB-Kelch protein, KLHL7, cause autosomal-dominant retinitis pigmentosa. PMID: 19520207

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Cold-induced sweating syndrome 3 (CISS3); Retinitis pigmentosa 42 (RP42)
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 組織特異性:
    Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15646

    OMIM: 611119

    KEGG: hsa:55975

    STRING: 9606.ENSP00000343273

    UniGene: Hs.654817



主站蜘蛛池模板: 亚洲欧美v国产蜜芽tv| 久久国产欧美日韩精品| 99亚洲男女激情在线观看| 午夜无码片在线观看影院| 中文无码精品a∨在线观看不卡| 日本少妇高潮喷水免费可以看| 亚洲精品国产自在现线最新| 国产精品免费久久久久电影| 久久综合香蕉国产蜜臀av| 酒店大战丝袜高跟鞋人妻| 亚洲国产综合无码一区| 亚洲欧洲日产韩国无码| 亚洲爆乳aaa无码专区| 久久久久99精品成人片试看 | 欧美精品亚洲精品日韩专区va | 国产亚洲精品俞拍视频| 9l国产精品久久久久尤物| 亚洲欧洲成人av每日更新 | 国产精品亚洲а∨无码播放不卡| 久久久久久久久久久久久9999| 蜜臀av人妻国产精品建身房| 国产玉足脚交极品在线播放| 久久精品国产一区二区免费| 国内精品一区二区三区| 国产乱码精品一区二区三区中文| 日日噜噜夜夜狠狠久久丁香五月 | 成人乱人伦视频在线观看| 狠狠躁夜夜躁无码中文字幕| 免费观看日本污污ww网站| 色偷偷色噜噜狠狠网站久久| 日本理伦片午夜理伦片| 婷婷色爱区综合五月激情| 99c视频色欲在线| 五月丁香六月综合缴清无码| 忘忧草社区中文字幕www| 久久久国产精品无码一区二区| 大胆欧美熟妇xx| 狠狠色综合7777久夜色撩人| 在线岛国片免费无码av| 成年黄页网站大全免费无码| 国产在线观看无码免费视频|