在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLF12 Antibody

  • 中文名稱:
    KLF12兔多克隆抗體
  • 貨號:
    CSB-PA897495LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: Mouse kidney tissue, Rat liver tissue, Rat brain tissue
      All lanes: KLF12 antibody at 2.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 45, 29, 34 kDa
      Observed band size: 45 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KLF12 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KLF12
  • 別名:
    2700063E05Rik antibody; AI225908 antibody; AI315654 antibody; AP-2 repressor antibody; AP-2rep antibody; AP-2rep transcription factor antibody; AP2REP antibody; B130052C06Rik antibody; D530033K05Rik antibody; HSPC122 antibody; KLF12 antibody; KLF12 zinc finger transcriptional repressor antibody; KLF12_HUMAN antibody; Krueppel like factor 12 antibody; Krueppel-like factor 12 antibody; OTTHUMP00000018503 antibody; Transcriptional repressor AP 2rep antibody; Transcriptional repressor AP-2rep antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse, Rat
  • 免疫原:
    Recombinant Human Krueppel-like factor 12 protein (36-313AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,KLF12 Antibody (CSB-PA897495LA01HU),的標記方式是Non-conjugated。對于KLF12 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA897495LB01HU KLF12 Antibody, HRP conjugated ELISA
    FITC CSB-PA897495LC01HU KLF12 Antibody, FITC conjugated
    Biotin CSB-PA897495LD01HU KLF12 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
  • 基因功能參考文獻:
    1. Results confirmed that KLF12 was highly expressed in nasopharyngeal carcinoma (NPC) tissues, and over-expressed KLF12 promoted NPC cell proliferation, while silencing KLF12 suppressed it. Furthermore, KLF12 was found to be a direct target for miR-1207 at its 3'-UTR mRNA. PMID: 30243935
    2. Data indicate Kruppel-like factor 12 protein (KLF12) as a metastasis-suppressor gene whose loss of function is associated with anoikis resistance through control of the cell cycle. PMID: 26455320
    3. KLF12 promotes tumor growth by directly activating early growth response protein 1 (EGR1). The levels of KLF12 and EGR1 correlate synergistically with a poor prognosis. These results indicate that KLF12 likely plays an important role in CRC and could serve as a potential prognostic marker and therapeutic target. PMID: 27442508
    4. the overexpression of miR-141 augments anoikis resistance in ovarian cancer cells by targeting and repressing the expression of KLF12, which, in turn, competes for binding sites in the survivin promoter with Sp1. The subsequent increase in survivin then protects ovarian cancer cells against anoikis by blocking the intrinsic apoptotic activity. PMID: 28095864
    5. Data show Kruppel-like factor 12 (KLF12) impairs endometrial decidualization by transcriptionally repressing Nur77 protein, and Nur77 overexpression reverses the poor decidual response of endometrial stromal cells (hESCs) in recurrent implantation failure (RIF) patients. PMID: 28359310
    6. SLC29A1 rs760370 and KLF12 rs9543524 SNPs are associated with treatment induced thrombocytopenia in chronic hepatitis C patients treated with PEGIFN2b/ribavirin/combination. PMID: 26750805
    7. our results supported that miR-205 was a miR specific to basal-like breast carcinoma (BLBC). which functioned as tumor suppressor gene through directly targeting and negatively regulating proto-oncogene KLF12. miR-205 dysregulation was involved in invasion and apoptosis. miR-205 and KLF12 provided a potential diagnosis biomarker and therapeutic approach for BLBC. PMID: 27278159
    8. Overexpression of KLF12 is associated with gastric cancer. PMID: 27468717
    9. Elevated KLF12 expression was accompanied by decreased FOXO1 expression in the endometria of patients with repeated implantation failure. PMID: 26223982
    10. overexpression of KLF12 in endometrial stromal cells significantly repressed the expression and secretion of decidualization biomarker genes and their products decidual prolactin and insulin-like growth factor binding protein-1 PMID: 23458459
    11. The KLF12 rs1324913 A allele homozygous genotype is a possible predictor of Rheumatoid Arthritis. PMID: 22150086
    12. no association of genetic polymorphism with rheumatoid arthritis in Spanish and Dutch cohorts PMID: 21658422
    13. In a large UK cohort of patients with rheumatoid arthritis, results have failed to add to the evidence for association at the KLF12 locus reported to be associated with rheumatoid arthritis in independent Spanish cohorts. PMID: 19907058
    14. KLF12 as a new susceptibility gene for rheumatoid arthritis. PMID: 18668548
    15. Overexpression of Kruppel-like factor 12 is associated with gastric cancer progression. PMID: 19588488

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Sp1 C2H2-type zinc-finger protein family
  • 數據庫鏈接:

    HGNC: 6346

    OMIM: 607531

    KEGG: hsa:11278

    STRING: 9606.ENSP00000366894

    UniGene: Hs.373857



主站蜘蛛池模板: 亚洲欧美成人一区二区三区| 妺妺跟我一起洗澡没忍住| 无线日本视频精品| 国产午夜精品一区二区三区漫画| 亚洲欧美国产va在线播放| 国产精品一区二区av在线观看 | 2022一本久道久久综合狂躁| 97人妻天天摸天天爽天天| 欧美三级不卡在线观看| 8x福利精品第一导航| 午夜性刺激在线视频免费| 国产v在线在线观看视频免费 | 解开人妻的裙子猛烈进入| 乱人伦无码中文视频在线| 国产精品55夜色66夜色| av免费网站在线观看| 久久久久人妻一区精品色欧美| 国产片精品av在线观看夜色 | 国产成人av无码精品| 久久精品国产亚洲a片高清不卡| 中文国产成人精品久久久| 免费人成小说在线观看网站| 国产一三四2021不卡| 亚洲综合色婷婷七月丁香 | 在线精品亚洲第一区焦香| 一本一道波多野结衣av中文| 西西人体444www大胆无码视频| 国产精品特黄aaaa片在线观看| 色偷偷色噜噜狠狠网站年轻人| 妺妺窝人体色www在线下载| 99er国产这里只有精品视频免费| 狠狠色狠狠色狠狠五月| 国产精品一区二区无线| 无码av免费毛片一区二区| 国产精品va尤物在线观看| 人人爽人人爽人人片av亚洲| 18禁网站免费无遮挡无码中文 | 欧美叉叉叉bbb网站| 国产麻豆精品传媒av国产婷婷| 日韩视频 中文字幕 视频一区 | 亚洲中文字幕乱码电影|