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  4. KIF21B Antibody

KIF21B Antibody

  • 中文名稱：
    KIF21B兔多克隆抗體
  • 貨號：
    CSB-PA012324LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA012324LA01HU diluted at 1:300 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KIF21B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KIF21B
  • 別名：
    KI21B_HUMAN antibody; KIAA0449 antibody; KIF21B antibody; Kinesin-like protein KIF21B antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Kinesin-like protein KIF21B protein (829-986AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，KIF21B Antibody (CSB-PA012324LA01HU)，的標記方式是Non-conjugated。對于KIF21B Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA012324LB01HU KIF21B Antibody, HRP conjugated ELISA
    FITC CSB-PA012324LC01HU KIF21B Antibody, FITC conjugated
    Biotin CSB-PA012324LD01HU KIF21B Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface.
  • 基因功能參考文獻：
    1. Thus, KIF21B combines microtubule-binding and regulatory activities that together constitute an autonomous microtubule pausing factor. PMID: 28290984
    2. KIF21B is associated with ankylosing spondylitis in a Chinese population of Shandong Province PMID: 25149646
    3. KIF21B may play an important role in the pathogenesis of AS in the Chinese population and might be a new therapeutic target for AS. PMID: 24065353
    4. Data show the association of SNPs in KIF21B with multiple sclerosis in a Belgian study population. PMID: 20587413
    5. Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B as susceptibility loci PMID: 20007504

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  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cell projection, dendrite. Cell projection, growth cone. Cell projection, axon. Cytoplasmic vesicle.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
  • 數據庫鏈接：

    HGNC: 29442

    OMIM: 608322

    KEGG: hsa:23046

    STRING: 9606.ENSP00000328494

    UniGene: Hs.169182



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