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  4. KIAA0319L Antibody

KIAA0319L Antibody

  • 中文名稱：
    KIAA0319L兔多克隆抗體
  • 貨號：
    CSB-PA012182GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    KIAA0319L
  • 別名：
    Dyslexia-associated protein KIAA0319-like protein antibody; K319L_HUMAN antibody; KIAA0319 like antibody; KIAA0319L antibody; KIAA1837 antibody; PKD1 like antibody; Polycystic kidney disease 1 like antibody; Polycystic kidney disease 1 related antibody; PP791 antibody; RP4 765A10.3 antibody; Uncharacterized protein KIAA0319 like antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Human KIAA0319L
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Possible role in axon guidance through interaction with RTN4R.; (Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system.
  • 基因功能參考文獻：
    1. Optic nerve damage may change retinal architecture to allow greater penetration of an AAV2 virus to transduce several additional cell types in the inner nuclear layer. PMID: 29204649
    2. AAVR directly binds to AAV2 particles, and that anti-AAVR antibodies efficiently block AAV2 infection; moreover, genetic ablation of AAVR renders a wide range of mammalian cell types highly resistant to AAV2 infection PMID: 26814968
    3. Results identify KIAA0319L as novel susceptibility loci for Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). KIAA0319L was overexpressed in peripheral blood cells of SSc and SLE patients compared with healthy controls. PMID: 23740937
    4. KIAA0319L remains an intriguing positional and functional candidate for RD, especially when considered alongside the supporting evidence for its homolog KIAA0319 on chromosome 6p. PMID: 19085271
  • 亞細胞定位：
    Cytoplasmic granule membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 組織特異性：
    Expressed in cortical neurons in the brain cortex (at protein level).
  • 數據庫鏈接：

    HGNC: 30071

    OMIM: 613535

    KEGG: hsa:79932

    STRING: 9606.ENSP00000318406

    UniGene: Hs.456507



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