KDM5C Antibody
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中文名稱:KDM5C兔多克隆抗體
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貨號:CSB-PA798835
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規格:¥1100
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圖片:
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The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA798835(KDM5C Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA798835(KDM5C Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他:
產品詳情
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Uniprot No.:
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基因名:KDM5C
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宿主:Rabbit
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反應種屬:Human
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免疫原:Synthetic peptide of Human KDM5C
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免疫原種屬:Homo sapiens (Human)
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標記方式:Non-conjugated
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抗體亞型:IgG
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純化方式:Antigen affinity purification
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式:Liquid
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應用范圍:ELISA,IHC
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推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:10000 IHC 1:30-1:150 -
Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能:Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.
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相關疾病:Mental retardation, X-linked, syndromic, Claes-Jensen type (MRXSCJ)
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亞細胞定位:Nucleus.
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蛋白家族:JARID1 histone demethylase family
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組織特異性:Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.
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數據庫鏈接:
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