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KCTD7 Antibody

  • 中文名稱:
    KCTD7兔多克隆抗體
  • 貨號:
    CSB-PA850395LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunofluorescence staining of A549 cells with CSB-PA850395LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) KCTD7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    KCTD7
  • 別名:
    KCTD7 antibody; BTB/POZ domain-containing protein KCTD7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human BTB/POZ domain-containing protein KCTD7 protein (5-152AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,KCTD7 Antibody (CSB-PA850395LA01HU),的標記方式是Non-conjugated。對于KCTD7 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA850395LB01HU KCTD7 Antibody, HRP conjugated ELISA
    FITC CSB-PA850395LC01HU KCTD7 Antibody, FITC conjugated
    Biotin CSB-PA850395LD01HU KCTD7 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in the control of excitability of cortical neurons.
  • 基因功能參考文獻:
    1. KCTD7 has an impact on K+ fluxes, neurotransmitter synthesis and neuronal function, and that malfunction of the encoded protein may lead to progressive myoclonus epilepsy. PMID: 27742667
    2. reviews the phenotype of progressive myoclonic epilepsy associated with KCTD7 mutations [review] PMID: 27629772
    3. This study identified that novel KCTD7 mutation in patients with progressive myoclonus epilepsy with ataxia. PMID: 25060828
    4. The KCTD7 gene, previously associated with progressive myoclonus epilepsies (PMEs) in a single inbred family, was screened for mutations in 18 Turkish PME patients. PMID: 22693283
    5. this study clearly demonstrates that KCTD7 mutations also cause a rare, infantile-onset NCL subtype designated as CLN14. PMID: 22748208
    6. We found a C to T mutation in exon 2 of the potassium channel tetramerization domain containing 7 gene(KCTD7)in a progressive myoclonic epilepsy family affecting a highly conserved segment of the predicted protein changing an arginine codon to a stop. PMID: 17455289

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  • 相關疾病:
    Epilepsy, progressive myoclonic 3, with or without intracellular inclusions (EPM3)
  • 亞細胞定位:
    Cell membrane. Cytoplasm, cytosol.
  • 數據庫鏈接:

    HGNC: 21957

    OMIM: 611725

    KEGG: hsa:154881

    UniGene: Hs.546627



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