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  4. KCNRG Antibody

KCNRG Antibody

  • 中文名稱：
    KCNRG兔多克隆抗體
  • 貨號：
    CSB-PA847638LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA847638LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCNRG Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCNRG
  • 別名：
    KCNRG antibody; CLLD4Potassium channel regulatory protein antibody; Potassium channel regulator antibody; Protein CLLD4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Potassium channel regulatory protein (1-229AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，KCNRG Antibody (CSB-PA847638LA01HU)，的標記方式是Non-conjugated。對于KCNRG Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA847638LB01HU KCNRG Antibody, HRP conjugated ELISA
    FITC CSB-PA847638LC01HU KCNRG Antibody, FITC conjugated
    Biotin CSB-PA847638LD01HU KCNRG Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes.
  • 基因功能參考文獻：
    1. The haploinsufficiency of KCNRG might be relevant to the progression of chronic lymphocytic leukemia (CLL)and multiple myeloma(MM) at least in a subset of patients. PMID: 20237900
    2. KCNRG is an ER-associated protein, which is proposed to regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes. PMID: 19968958
    3. the primary characterization of a new gene KCNRG mapped at chromosome band 13q14.3; is a candidate for a B-cell chronic lymphocytic leukemia and prostate cancer tumor suppressor gene PMID: 12650944
    4. Results suggest that genetic alterations and the expression of KCNRG might play an important role in the development and/or progression of a subset of hepatocellular carcinoma. PMID: 16819283
    5. Autoantibodies to KCNRG were present in 7 of the 8 patients with respiratory symptoms in autoimmune polyendocrine syndrome type 1 PMID: 19251657
    6. KCNRG suppresses K+ channel activity in human prostate cell line LNCaP. PMID: 12650944

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  • 亞細胞定位：
    Endoplasmic reticulum.
  • 組織特異性：
    Ubiquitous in normal tissues and expressed in some tumor tissues.
  • 數據庫鏈接：

    HGNC: 18893

    OMIM: 607947

    KEGG: hsa:283518

    STRING: 9606.ENSP00000324191

    UniGene: Hs.660161



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