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  4. KCNH7 Antibody, HRP conjugated

KCNH7 Antibody, HRP conjugated

  • 中文名稱：
    KCNH7兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA878877LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KCNH7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KCNH7
  • 別名：
    KCNH7 antibody; ERG3Potassium voltage-gated channel subfamily H member 7 antibody; Ether-a-go-go-related gene potassium channel 3 antibody; ERG-3 antibody; Eag-related protein 3 antibody; Ether-a-go-go-related protein 3 antibody; hERG-3 antibody; Voltage-gated potassium channel subunit Kv11.3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Potassium voltage-gated channel subfamily H member 7 protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
  • 基因功能參考文獻：
    1. we have discovered that, the Kv11.3 (hERG3) a plasma-membrane potassium channel plays a critical role in the regulation of autophagy in a melanoma cell model PMID: 26942884
    2. KCNH7 c.1181G>A had the highest enrichment among individuals with bipolar spectrum disorder (x2 5 7.3) and the strongest family-based association with bipolar 1 (P 5 0.021), bipolar spectrum (P 5 0.031) and any major affective disorder (P 5 0.016). PMID: 24986916
    3. The recombinant wild-type ERG3 protein produced in HEK cells generates two prominent bands. When the entire CNBD of ERG3 protein was deleted, only an EndoH-sensitive band was generated, indicating that this band constitutes the immature species. PMID: 15961404
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.3/KCNH7 sub-subfamily
  • 組織特異性：
    Expressed in prolactin-secreting adenomas.
  • 數據庫鏈接：

    HGNC: 18863

    OMIM: 608169

    KEGG: hsa:90134

    STRING: 9606.ENSP00000331727

    UniGene: Hs.657413



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