在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KAP95 Antibody

KAP95 Antibody

  • 中文名稱：
    KAP95 Antibody
  • 貨號：
    CSB-PA012490XA01SVG
  • 規格：
    ￥880
  • 圖片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes:KAP95 Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 34.6 kDa
      Observed band size: 34 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) KAP95 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KAP95
  • 別名：
    Importin subunit beta-1 (Importin-95) (Karyopherin subunit beta-1) (Karyopherin-95) KAP95 YLR347C L8300.15
  • 宿主：
    Rabbit
  • 反應種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 免疫原：
    Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) KAP95 protein (611-861aa)
  • 免疫原種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Importin beta subunit that functions in nuclear protein import through association with the importin alpha subunit, which binds to the classical nuclear localization signal (cNLS) in cargo substrates. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by importin beta through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, GTP-Ran binds to importin beta and the three components separate, leading to release of the cargo. Importin alpha and beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin beta. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of histones H2A and H2B. Mediates the nuclear import of transcription factor GCN4.
  • 基因功能參考文獻：
    1. Data suggest that, in nuclear exosomes, karyopherins are bound to the Rrp6 complex; Srp1, Kap95, and Sxm1 appear to be the most important karyopherins for nuclear import of Rrp6. (Rrp6 = exosome nuclease subunit RRP6; Srp1 = karyopherin alpha kap60; Kap95 = karyopherin beta Kap95; Sxm1 = karyopherin Kap108) PMID: 28539363
    2. The Kap95 is able to mediate efficient Mig2-Kap95 interaction in the absence of the importin-alpha. PMID: 23131016
    3. Hxk2 as a new cargo for the alpha/beta-importin pathway of S. cerevisiae. PMID: 22157003
    4. Kap95 is likely the primary karyopherin responsible for Replication protein A nuclear import in yeast. PMID: 21332387
    5. The authors identified karyopherin Kap95 as the transport factor responsible for the nuclear import of Slt2 and Rlm1. PMID: 19930464
    6. identification of a key interaction site where the RanGTP switch I loop binds to the carboxy-terminal arch of Kap95p PMID: 15864302
    7. There is a correlation between the binding affinity of an NLS cargo for the NLS receptor, importin alpha, and the import rate for this cargo. PMID: 16785238
    8. Kap95 serves as a key regulator of nuclear pore complex assembly into intact nuclear envelopes. PMID: 17182855
    9. Data show the crystal structure of the Kap95p-RanGDP complex shows that Kap95p induces the switch I and II regions of RanGDP to adopt a conformation that resembles that of the GTP-bound form. PMID: 18708071
    10. Pct1 interacts with Kap60 and Kap95 with this tripartite complex transiting the nuclear pore. PMID: 19141610

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Nucleus, nuclear pore complex.
  • 蛋白家族：
    Importin beta family, Importin beta-1 subfamily
  • 數據庫鏈接：

    KEGG: sce:YLR347C

    STRING: 4932.YLR347C



主站蜘蛛池模板： 亚洲理论在线a中文字幕| 免费无码一区二区三区a片百度| 真人二十三式性视频(动)| 国产色无码精品视频国产| 亚洲 激情 小说 另类 欧美| 黑人巨大videos精品| 真人一进一出120秒试看| 在线看片国产日韩欧美亚洲| 亚洲日韩久久综合中文字幕| 成人国产欧美大片一区| 国产免费一卡二卡三卡四卡| 久久无码超清激情av| 最近最新中文字幕高清免费| 国产亚洲视频中文字幕97精品| 两根大肉大捧一进一出好爽视频| 免费国产白丝喷水娇喘视频| 免费无码黄十八禁网站在线观看| 人妻少妇偷人精品视频| 欧美激情性做爰免费视频| 亚洲处破女av日韩精品| 综合激情亚洲丁香社区| 亚洲人成小说网站色| 欧美寡妇xxxx黑人猛交| 亚洲乱码中文字幕综合| 西西人体大胆瓣开下部毛茸茸| 樱花草在线社区www日本影院| 亚洲va中文字幕无码一二三区| 成人丝袜激情一区二区| 亚洲国产精品无码久久久久高潮| 日本www一道久久久免费| 亚洲最大的熟女水蜜桃av网站| 久久不见久久见免费视频7| 成人免费一区二区三区视频| 欧美猛少妇色xxxxx猛交| 人人爽人人澡人人人人妻| 一本加勒比波多野结衣| 曰韩少妇内射免费播放| 久久久久国产精品人妻aⅴ牛牛 | 国产精品久久久一区二区三区 | 伊人久久大香线蕉亚洲五月天| 黄网站欧美内射|