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  4. JRK Antibody

JRK Antibody

  • 中文名稱：
    JRK兔多克隆抗體
  • 貨號：
    CSB-PA525639NA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: SH-SY5Y whole cell lysate, Mouse heart tissue
      All lanes: JRK antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 62, 63 kDa
      Observed band size: 62 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) JRK Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    JRK
  • 別名：
    JRK antibody; JH8 antibody; Jerky protein homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Peptide sequence from Human Jerky protein homolog protein (465-483AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，JRK Antibody (CSB-PA525639NA01HU)，的標記方式是Non-conjugated。對于JRK Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA525639NB01HU JRK Antibody, HRP conjugated ELISA
    FITC CSB-PA525639NC01HU JRK Antibody, FITC conjugated
    Biotin CSB-PA525639ND01HU JRK Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May bind DNA.
  • 基因功能參考文獻：
    1. JRK expression was aberrantly elevated in 21% of colorectal cancers, 15% of breast and ovarian cancers and was associated with increased expression of beta-catenin target genes and increased cell proliferation PMID: 26455321
    2. in the adult intestine, Ebd acts independently of Ewg in physiological Wnt signaling, but cooperates with Ewg to induce the hyperactivation of Wnt target gene expression following Apc1 loss. These findings have relevance for human tumorigenesis, as Jerky (JRK/JH8), the human Ebd homolog, promotes Wnt pathway hyperactivation and is overexpressed in colorectal, breast, and ovarian cancers PMID: 28708826
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Tigger transposable element derived protein family
  • 組織特異性：
    Expressed ubiquitously.
  • 數據庫鏈接：

    HGNC: 6199

    OMIM: 603210

    KEGG: hsa:8629

    UniGene: Hs.535903



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