在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. JDP2 Antibody

JDP2 Antibody

  • 中文名稱：
    JDP2兔多克隆抗體
  • 貨號：
    CSB-PA006988
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using JDP2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    JDP2
  • 別名：
    Jdp2 antibody; JDP2_HUMAN antibody; Jun dimerization protein 2 antibody; JUNDM2 antibody; Progesterone receptor co-activator antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from Human JDP2 around the non-phosphorylation site of T148.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

引用文獻

產品評價

靶點詳情

  • 功能：
    Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
  • 基因功能參考文獻：
    1. In hepatocellular carcinoma, high expression of JDP2 is significantly correlated with smaller tumor size, early stage HCC and better survival. PMID: 28315425
    2. Preeclamptic plasma induces transcription modifications involving the AP-1 transcriptional regulator JDP2 in endothelial cells. PMID: 24120378
    3. Results suggest that JDP2 is an integral component of the Nrf2-MafK complex and that it modulates antioxidant and detoxification programs by acting via the ARE. PMID: 24232097
    4. the recruitment of multiple HDAC members to JDP2 and ATF3 is part of their transcription repression mechanism. PMID: 22989952
    5. The molecular mechanisms that underlie the action of JDP2 in cellular aging and replicative senescence by mediating the dissociation of polycomb repressive complexes from the p16(Ink4a)/Arf locus are discussed. PMID: 20950777
    6. JDP2 is crucial to triggering reactivation from latency to lytic replication PMID: 21525011
    7. 3 SNPs (2 intronic: rs741846 & rs175646; & 1 in the untranslated region: rs8215) & their genotype distribution showed significant association in the Japanese & Korean but not Dutch intracranial aneurysm patients. PMID: 20452405
    8. JDP2 expression was downregulated in pancreatic carcinoma & this correlated with metastasis & decreased post-surgery survival. PMID: 20677166
    9. c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene PMID: 14627710
    10. JDP2 is a cellular survival protein whose presence is necessary for normal cellular function PMID: 16026868
    11. JDP2 acts as a repressor and could be functionally associated with HDAC3 to inhibit CHOP transcription PMID: 18396163
    12. IRF2-BP1 is a JDP2-binding protein enhancing the polyubiquitination of JDP2 and represses ATF2-mediated transcriptional activation from a CRE-containing promoter. PMID: 18671972
    13. A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain. PMID: 19553667

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    BZIP family, ATF subfamily
  • 數據庫鏈接：

    HGNC: 17546

    OMIM: 608657

    KEGG: hsa:122953

    STRING: 9606.ENSP00000267569

    UniGene: Hs.196482



主站蜘蛛池模板： 宅宅午夜无码一区二区三区| 国产精自产拍久久久久久蜜| 热re99久久精品国产66热| 亚洲成在人线av无码| 欧亚乱熟女一区二区三区在线| 亚洲大码熟女在线观看| 人妻无码中字在线a| 久久这里精品国产99丫e6| 亚洲国产成人久久一区二区三区| 国产亚洲人成在线播放| 亚洲无人区午夜福利码高清完整版| 大伊香蕉精品视频在线直播| 国产综合无码一区二区色蜜蜜 | 亚洲欧洲无码一区二区三区| 国产熟妇午夜精品aaa| 男女做爰猛烈啪啪吃奶伸舌头下载 | 亚洲人成日韩中文字幕无卡| 福利cosplayh裸体の福利| 无码色偷偷亚洲国内自拍| 亚洲欧美综合成人五月天网站| 日韩亚洲国产高清免费视频| 狠狠色狠狠色综合| 亚洲a成人片在线观看 | 国产美女裸体丝袜喷水视频| 2022国产日产欧产精品| 激情 小说 亚洲 图片 伦| 西西人体大胆4444www| 亚洲 欧美 自拍 美腿 卡通| 一区二区三区无码免费看| 伊人久久久精品区aaa片| 日本道色综合久久影院| 少妇乳大丰满在线播放| 亚洲精品gv天堂无码男同| 国产精品亚洲欧美大片在线看| 国产欧美日韩综合视频专区| 四虎永久在线精品免费无码| 亚洲国产欧美在线人成app| 亚洲成av人在线视| 免费看成人aa片无码视频| 中文字幕人妻被公上司喝醉506| 国产精品 视频一区 二区三区|