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  4. ISX Antibody

ISX Antibody

  • 中文名稱：
    ISX兔多克隆抗體
  • 貨號：
    CSB-PA011854LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA011854LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA011854LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ISX Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ISX
  • 別名：
    DKFZp781N2395 antibody; Intestine-specific homeobox antibody; Isx antibody; ISX_HUMAN antibody; MGC138417 antibody; OTTHUMP00000028558 antibody; Pancreas intestine homeodomain transcription factor antibody; Pix 1 antibody; RAX like homeobox antibody; RAX-like homeobox antibody; RAXLX antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Intestine-specific homeobox protein (1-245AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，ISX Antibody (CSB-PA011854LA01HU)，的標記方式是Non-conjugated。對于ISX Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA011854LB01HU ISX Antibody, HRP conjugated ELISA
    FITC CSB-PA011854LC01HU ISX Antibody, FITC conjugated
    Biotin CSB-PA011854LD01HU ISX Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
  • 基因功能參考文獻：
    1. our results indicate that E2F1 is an important downstream gene of ISX in hepatoma progression. PMID: 27175585
    2. Results show that ISX expression mediated AHR-induced tumorigenesis in hepatocellular carcinoma. PMID: 28398627
    3. Overall, our results identified a feed-forward mechanism of immune suppression in hepatocellular carcinoma organized by ISX, which involves kynurenine-AHR signaling and PD-L1, offering insights into immune escape by hepatocellular carcinoma PMID: 28625979
    4. ISX expression induced by H. pylori infection may lead to intestinal metaplasia and hyperproliferation of gastric mucosa through CDX1/2 and cyclinD1 expression, contributing to gastric carcinogenesis. PMID: 26872890
    5. Genetics and diet regulate vitamin A production via the homeobox transcription factor ISX PMID: 23393141
    6. our results highlight ISX as an important regulator in hepatoma progression with significant potential as a prognostic and therapeutic target in HCCs. PMID: 23221382

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  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 28084

    OMIM: 612019

    KEGG: hsa:91464

    STRING: 9606.ENSP00000311492

    UniGene: Hs.567637



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