在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. INTS6 Antibody, Biotin conjugated

INTS6 Antibody, Biotin conjugated

  • 中文名稱：
    INTS6兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA011764LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) INTS6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    INTS6
  • 別名：
    DBI 1 antibody; DBI-1 antibody; DBI1 antibody; DDX26 antibody; DDX26A antibody; DEAD box protein antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26 antibody; Deleted in cancer 1 antibody; DICE1 antibody; DKFZp434B105 antibody; HDB antibody; Int6 antibody; INT6_HUMAN antibody; Integrator complex subunit 6 antibody; INTS 6 antibody; ints6 antibody; Notchl2 antibody; OTTHUMP00000018439 antibody; OTTHUMP00000215034 antibody; OTTHUMP00000215036 antibody; Protein DDX26 antibody; Protein deleted in cancer 1 antibody; RNA helicase HDB antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Integrator complex subunit 6 protein (571-795AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. May have a tumor suppressor role; an ectopic expression suppressing tumor cell growth.
  • 基因功能參考文獻：
    1. DICE1 appears to be involved in prostate cancer progression rather than in the initiation of prostate cancer. PMID: 25660097
    2. Findings demonstrate INTS6P1 and INTS6 exert the tumor suppressive roles through competing for oncomiR-17-5p. PMID: 25686840
    3. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites. PMID: 23986477
    4. Findings suggest that EBV encoded miR-BART3* miRNA targets DICE1 tumor suppressor to promote cellular growth and transformation in nasopharyngeal cancer(NPC). PMID: 23280823
    5. Molecular characterization of the tumor suppressor gene in lung carcinoma cells PMID: 11939413
    6. Somatic mutations were identified in three patients (3/56, 5%), and one novel polymorphism was identified in 3% of ESCC patients (4/136) and 3% of healthy individuals (6/232). We conclude that DICE1 mutations occur in ESCC but are infrequent. PMID: 12527901
    7. DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I signaling PMID: 15254679
    8. Not mutated in human cancer cell lines which demonstratse 13q14 deletions. PMID: 16271964

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Integrator subunit 6 family
  • 組織特異性：
    Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 數據庫鏈接：

    HGNC: 14879

    OMIM: 604331

    KEGG: hsa:26512

    STRING: 9606.ENSP00000310260

    UniGene: Hs.439440



主站蜘蛛池模板： 精品无码国产一区二区三区麻豆| 成人免费无码不卡毛片视频| 中文在线www天堂网| 国产精品v欧美精品v日韩精品| 中文字幕欧美人妻精品一区| 一区二区三区高清日本vr| 大ji巴好深好爽又大又粗视频| 人妻 校园 激情 另类| 又紧又大又爽精品一区二区| 亚洲一区二区三区在线观看网站| 女人爽到高潮视频免费直播| 国产精品久久久久久久久久免费看| 老熟妇仑乱视频一区二区| 国产人成网线在线播放va| 中文无码第3页不卡av| 无码人妻精品一二三区免费| 久久久精品中文字幕麻豆发布| 永久免费观看的毛片手机视频| 丰满少妇人妻hd高清大乳在线 | 131美女爱做视频国产福利| 久久人人爽爽爽人久久久| 国产女人高潮视频在线观看| 蜜芽av无码精品国产午夜| 99亚洲乱人伦aⅴ精品| 女人爽到高潮免费看视频| 宅男66lu国产在线观看| 中文资源在线天堂库8| 亚洲第一无码xxxxxx| 天堂中文8资源在线8| 日本妇人成熟免费中文字幕| 好爽好舒服要高潮了视频| 国产麻豆成人传媒免费观看| 偷看农村妇女牲交| 青楼妓女禁脔道具调教sm| 中文字字幕人妻中文| 午夜免费视频| 国产jjizz女人多水| 天天躁夜夜躁狠狠是什么心态| 久久精品人妻少妇一区二区三区 | 天天干天天日夜夜操| 男人的天堂av网站|