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INMT Antibody

  • 中文名稱：
    INMT兔多克隆抗體
  • 貨號：
    CSB-PA011723LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: INMT antibody at 2µg/ml + Mouse lung tissue
      Secondary
      Goat polyclonal to rabbit lgG at 1/15000 dilution
      Predicted band size: 29 kDa
      Observed band size: 29 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA011723LA01HU at dilution of 1:100
    • Immunofluorescence staining of A549 cells with CSB-PA011723LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) INMT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    INMT
  • 別名：
    Amine N methyltransferase antibody; Amine N-methyltransferase antibody; Aromatic alkylamine N methyltransferase antibody; Aromatic alkylamine N-methyltransferase antibody; Arylamine N methyltransferase antibody; Arylamine N-methyltransferase antibody; Indolamine N-methyltransferase antibody; Indolethylamine N methyltransferase antibody; Indolethylamine N-methyltransferase antibody; Inmt antibody; INMT_HUMAN antibody; nicotine N methyltransferase antibody; TEMT antibody; thioester S methyltransferase like antibody; Thioether S methyltransferase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Indolethylamine N-methyltransferase protein (1-263AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，INMT Antibody (CSB-PA011723LA01HU)，的標記方式是Non-conjugated。對于INMT Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA011723LB01HU INMT Antibody, HRP conjugated ELISA
    FITC CSB-PA011723LC01HU INMT Antibody, FITC conjugated
    Biotin CSB-PA011723LD01HU INMT Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds.
  • 基因功能參考文獻：
    1. study suggests that rs77743549 of INMT may be associated with the risk for Hirschsprung's disease PMID: 26183064
    2. genome-wide association studies in populations in Argentina/Bangladeshi: Three SNPs in INMT (rs6970396, rs1061644, rs4270015) are associated with production of trimethylselenonium (TMSe); urinary Se excretion is up-regulated in TMSe-producing women. PMID: 26537946
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family
  • 組織特異性：
    Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult a
  • 數據庫鏈接：

    HGNC: 6069

    OMIM: 604854

    KEGG: hsa:11185

    UniGene: Hs.632629



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