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  4. IL20RB Antibody

IL20RB Antibody

  • 中文名稱：
    IL20RB兔多克隆抗體
  • 貨號：
    CSB-PA740921ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA740921ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IL20RB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    DIRS1 antibody; Fibronectin type III domain containing 6 antibody; FNDC6 antibody; I20RB_HUMAN antibody; IL 20R beta antibody; IL 20R2 antibody; IL-20 receptor subunit beta antibody; IL-20R-beta antibody; IL-20R2 antibody; IL-20RB antibody; IL20RB antibody; Interleukin 20 receptor beta antibody; Interleukin 20 receptor beta chain precursor antibody; Interleukin 20 receptor II antibody; Interleukin-20 receptor subunit beta antibody; MGC34923 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Interleukin-20 receptor subunit beta protein (48-177AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
  • 基因功能參考文獻：
    1. Trabecular meshwork cells express IL-20 receptors; Mutation of the T104 residue in IL-20R2 leads to a reduction in STAT3 phosphorylation as well as decreased matrix metalloproteinase activity PMID: 24455976
    2. The crystal structure of the IL-20/IL-20R1/IL-20R2 complex reveals how type I and II complexes discriminate cognate from noncognate ligands PMID: 22802649
    3. The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis and single nucleotide polymorphisms (SNPs) in the IL20RA and IL20RB genes in psoriasis patients were investigated. PMID: 18480827
  • 亞細胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Type II cytokine receptor family
  • 組織特異性：
    Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.
  • 數據庫鏈接：

    HGNC: 6004

    OMIM: 605621

    KEGG: hsa:53833

    STRING: 9606.ENSP00000328133

    UniGene: Hs.61232



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