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IL20RA Antibody

  • 中文名稱:
    IL20RA兔多克隆抗體
  • 貨號:
    CSB-PA922324
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA922324(IL20RA Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA922324(IL20RA Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    class II cytokine receptor ZCYTOR7 antibody; CRF2 8 antibody; CRF2-8 antibody; Cytokine receptor class II member 8 antibody; Cytokine receptor class-II member 8 antibody; Cytokine receptor family 2 member 8 antibody; I20RA_HUMAN antibody; IL 20R alpha antibody; IL 20R1 antibody; IL-20 receptor subunit alpha antibody; IL-20R-alpha antibody; IL-20R1 antibody; IL-20RA antibody; IL20 Receptor alpha antibody; IL20RA antibody; Interleukin 20 receptor alpha chain antibody; Interleukin 20 receptor, alpha antibody; interleukin-20 receptor I antibody; Interleukin-20 receptor subunit alpha antibody; ZcytoR7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human IL20RA
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
  • 基因功能參考文獻:
    1. the DNA fragment containing the associated SNPs interacts through chromatin looping not only with TNFAIP3, but also with IL20RA, located 680 kb upstream. PMID: 27799070
    2. IL20R1 correlated with prognosis of patients with pancreatic cancer, and mediates pancreatic cancer cell growth and migration. It may be a potential biomarker for IL24 molecular-targeted therapy. PMID: 26977011
    3. crystallographic asymmetric unit contains one IL-20-IL-20R1-IL-20R2 complex, corresponding to a solvent content of approximately 54% PMID: 22232181
    4. IL-20RA polymorphisms may have a role in psoriasis PMID: 19926456
    5. Complete mda-7/IL-24 receptors (IL-22R1/IL-20R2 and IL-20R1/IL-20R2) are seldom expressed in liver cancer cell lines. PMID: 19666410
    6. forms stable complex with interleukin-19 and interleukin-20 [IL-20R1][IL-20R2] PMID: 14580208
    7. sensitivity to recombinant interleukin-26(IL-26) of various cell lines strictly correlated with the expression of IL-20 1 receptor and blocking antibodies against either IL-10 receptor 2 or IL-20 receptor 1 inhibited IL-26-dependent signal transduction PMID: 15178681
    8. The hypotheses that genetic variations of the IL-20-RI influence susceptibility to psoriasis was investigated. PMID: 18480827

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  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Type II cytokine receptor family
  • 組織特異性:
    Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin.
  • 數據庫鏈接:

    HGNC: 6003

    OMIM: 605620

    KEGG: hsa:53832

    STRING: 9606.ENSP00000314976

    UniGene: Hs.445868



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