在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IL11RA Antibody

IL11RA Antibody

  • 中文名稱：
    IL11RA兔多克隆抗體
  • 貨號(hào)：
    CSB-PA043792
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from HeLa cells, using IL11RA antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) IL11RA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from C-terminal of Human IL11RA.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.; Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.; Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
  • 基因功能參考文獻(xiàn)：
    1. The results presented here reveal an additional function in classic IL-11 signaling, highlighting the importance of the IL-11R stalk in IL-11 signaling PMID: 29523682
    2. The D2 domain of the IL-11R contains two N-linked glycans, which are dispensable for its biological activity, but differentially control maturation and intracellular trafficking of the receptor. PMID: 29533934
    3. High IL11RA expression is associated with endometrioid tumours. PMID: 28186993
    4. Report IL11RA and MELK amplification in gastric cancer cell lines and primary gastric adenocarcinomas. PMID: 27920471
    5. These results indicate that IL-11Ralpha is a potential target for the development of molecular targeted therapy and noninvasive tumor imaging in human osteosarcoma. PMID: 25524575
    6. IL11RA promoter polymorphism--rs1061758--may be associated with the risk of papillary thyroid cancer in the Korean population. PMID: 21982075
    7. data suggest that IL-11Ralpha-CAR T cells may represent a new therapy for patients with osteosarcoma pulmonary metastases PMID: 22075555
    8. IL11 as well as IL11RA are likely to play a role in the progression of endometrial carcinoma. PMID: 20553623
    9. IL-11Ralpha was expressed in both epithelial and stromal cells, with epithelial staining being more intense PMID: 12200462
    10. the interleukin-11 receptor alpha-chain has evidence of antiapoptotic effects in human colonic epithelial cells PMID: 14701802
    11. IL-11Ralpha is a candidate target for translational clinical trials against advanced and metastatic prostate cancer. PMID: 14744752
    12. interleukin-11 receptor is expressed in CD38-positive cells from patients with multiple myeloma PMID: 15512823
    13. High expression of interleukin-11 receptor alpha is associated with Hodgkin's lymphoma PMID: 16291580
    14. High interleukin 11 receptor is associated with breast cancer PMID: 16614887

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Craniosynostosis and dental anomalies (CRSDA)
  • 亞細(xì)胞定位：
    [Interleukin-11 receptor subunit alpha]: Membrane; Single-pass type I membrane protein.; [Soluble interleukin-11 receptor subunit alpha]: Secreted.; [Isoform HCR2]: Secreted.
  • 蛋白家族：
    Type I cytokine receptor family, Type 3 subfamily
  • 組織特異性：
    Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malig
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5967

    OMIM: 600939

    KEGG: hsa:3590

    STRING: 9606.ENSP00000326500

    UniGene: Hs.591088



主站蜘蛛池模板： 欧美 日本 国产 在线a∨观看| 精品一区二区三人妻视频| 免费国产成人高清在线视频| 国产成av人片在线观看无码| 波多野美乳人妻hd电影欧美| 女人被狂躁到高潮视频免费软件| 看国产黄大片在线观看| 精品无码综合一区二区三区| 欧美成人精品午夜免费影视| 牲交欧美兽交欧美| 亚洲精品国产suv一区| 狠狠色丁香久久婷婷综合图片| 亚洲综合在线视频自拍| 99亚洲精品自拍av成人| 亚洲中文字幕无码永久在线| 51久久成人国产精品麻豆| 成人片黄网站a毛片免费观看| 爽到高潮无码视频在线观看| 国产精品婷婷久久爽一下| 99久无码中文字幕一本久道| 国色天香精品一卡2卡3卡4| 国产精品美女久久久久| 成 人 免费观看网站| 成av人电影在线观看| 国产在线无码播放不卡视频 | 欧美真人性做爰一二区| 日本猛少妇色xxxxx猛叫| 亚洲的天堂av无码| 中文字幕中文有码在线| 国产av一区二区精品久久| 国产农村老太xxxxhdxx| 日本特黄特色特爽大片| 国产在线午夜不卡精品影院| 四虎精品成人a在线观看| 3d动漫精品啪啪一区二区免费| 女人张开双腿让男人猛桶| 欧美饥渴少妇xxxxx性| 一本一道久久a久久精品综合| 国产爆乳无码一区二区麻豆| 国产在线观看免费观看不卡| 思思99热久久精品在线6|