在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IKZF2 Antibody

  • 中文名稱:
    IKZF2兔多克隆抗體
  • 貨號:
    CSB-PA011576GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    IKZF2
  • 別名:
    ANF1A2 antibody; HELIOS antibody; IKAROS family zinc finger 2 antibody; Ikaros family zinc finger protein 2 antibody; IKZF 2 antibody; IKZF2 antibody; IKZF2_HUMAN antibody; MGC34330 antibody; Zinc finger DNA binding protein Helios antibody; Zinc finger protein Helios antibody; Zinc finger protein subfamily 1A 2 antibody; ZNF1A2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human IKZF2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Associates with Ikaros at centromeric heterochromatin.
  • 基因功能參考文獻:
    1. The results suggested that increased methylation of Foxp3 Treg-specific demethylated region sequence and altered Helios gene expression in peripheral whole blood may have a role in the pathogenesis of rheumatoid arthritis via their effects on Regulatory T cell stability. PMID: 29851536
    2. Helios mRNA is down-regulated in Treg cells of patients with hypertension. PMID: 30074152
    3. mRNA expression of Helios was decreased in CD4+ T cells from patients with acute coronary syndrome. PMID: 29259350
    4. High expression of TIGIT and Helios identifies CD4+ T cells with impaired immunological functions, primarily among patients with an advanced stage of Sezary syndrome. PMID: 27592800
    5. The results show that high vs. low expression of Nrp-1 or Helios does not unequivocally identify Treg clones of thymic or peripheral origin. PMID: 26495986
    6. Helios could be considered a more reliable marker for distinguishing thymic derived Regulatory T (tTreg) cells or peripherally induced Treg cells than Nrp1. PMID: 25586548
    7. expression is not affected in diGeorge syndrome PMID: 25008482
    8. Forkhead box protein 3(+) regulatory T cells and Helios(+) subset in perinatally acquired HIV. PMID: 25425428
    9. Ectopic expression of ATL-type Helios isoform as well as knockdown of normal Helios or Ikaros promoted T-cell growth. PMID: 23600753
    10. Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus. PMID: 23264341
    11. large number of ex vivo expanded functional Treg can be obtained from long-term T1D patients, although fewer expanded Treg expressed a high level of Helios PMID: 23409157
    12. A differential role for monocyte subsets in control of Helios(+/-) Treg development that is mediated by distinct inflammatory cytokines. PMID: 23365462
    13. Helios+ and Helios- cells coexist within the natural FOXP3+ T regulatory cell subset in humans. PMID: 23359504
    14. Presence of Helios-positive regulatory T (Treg) cells may maintain susceptibility to helminth infection on the C57BL/6 mouse background. PMID: 22753928
    15. Data found that Helios-negative T cells are enriched for naive T cell phenotypes and vice versa. Moreover, Helios can be induced during T cell activation and proliferation, but regresses in the same cells under resting conditions. PMID: 21918685
    16. Expanded peripheral FoxP3+ Tregs in untreated renal cell carcinoma patients co-express Helios. Interestingly, IL-2 administration results in expansion of FoxP3+Helios+ natural Tregs (nTregs) significantly more than FoxP3+Helios- iTregs. PMID: 21570917
    17. found that suppression of Helios message in CD4(+)CD25(+) T cells significantly attenuates their suppressive function. PMID: 20226531
    18. Novel short isoforms of Helios are overexpressed in a patient with T-cell acute lymphoblastic leukemia and may contribute to the development of T-cell malignancies. Data for unaltered Helios indicates tumor suppressor function. PMID: 11937265
    19. suggest a critical role for Helios in the mechanism of leukemogenesis PMID: 17297655

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Ikaros C2H2-type zinc-finger protein family
  • 數據庫鏈接:

    HGNC: 13177

    OMIM: 606234

    KEGG: hsa:22807

    STRING: 9606.ENSP00000410447

    UniGene: Hs.604950



主站蜘蛛池模板: 国产av国片精品| 精品一区二区三区在线播放视频| 99久久精品费精品国产一区二区| 女子spa高潮呻吟抽搐| 免费观看的av在线播放| 亚洲中文字幕久久精品蜜桃| 久久天堂av综合合色| 无码国产伦一区二区三区视频| 日本无翼乌邪恶大全彩h| 久久三级中文欧大战字幕| 国产精品玩偶在线观看| 亚洲中文字幕无码爆乳av | 久久不见久久见免费影院www日本| 国内永久福利在线视频图片| 正在播放国产乱子伦最新视频 | 丰满人妻被黑人连续中出| 乱色熟女综合一区二区三区| 日本一道综合久久aⅴ久久| 国产成人精品视频国产| 欧美精品一区二区黄a片| 国产成a人片在线观看视频下载| 久久综合给合久久狠狠狠88| 日本一卡2卡3卡4卡免费乱码网站| 国产露脸150部国语对白| 欧美变态另类牲交zozo| 久久视频在线视频精品| 久久精品人妻无码专区| 国产网友自拍在线视频| 色又黄又爽18禁免费视频| 日日碰狠狠躁久久躁9| 蜜臀av夜夜澡人人爽人人| 欧美性猛交xxxx乱大交丰满| 被技师按摩到高潮的少妇| 国产激情一区二区三区| 久久www免费人成精品| 成人影院yy111111在线| 久久国产福利国产秒拍飘飘网| 日本一本二本三区免费| 黄网站色成年片在线观看| 欧洲亚洲色视频综合在线 | 精品久久国产综合婷婷五月|