在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IGHM Antibody

  • 中文名稱:
    IGHM兔多克隆抗體
  • 貨號:
    CSB-PA582625
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HEPG2 cells using IgM Chain C Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    IGHM
  • 別名:
    IGHMImmunoglobulin heavy constant mu antibody; Ig mu chain C region antibody; Ig mu chain C region BOT antibody; Ig mu chain C region GAL antibody; Ig mu chain C region OU antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from IgM Chain C at AA range: 391-440
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB,ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:10000-20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. IgM antibodies play an important role in primary defense mechanisms. They have been shown to be involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The membrane-bound form is found in the majority of normal B-cells alongside with IgD. Membrane-bound IgM induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. It may cause death of cells by apoptosis. It is also found in soluble form, which represents about 30% of the total serum immunoglobulins where it is found almost exclusively as a homopentamer. After the antigen binds to the B-cell receptor, the secreted form is secreted in large amounts.
  • 相關(guān)疾病:
    Agammaglobulinemia 1, autosomal recessive (AGM1)
  • 亞細胞定位:
    [Isoform 1]: Secreted. Note=During differentiation, B-lymphocytes switch from expression of membrane-bound IgM to secretion of IgM.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5541

    OMIM: 147020

    UniGene: Hs.510635



主站蜘蛛池模板: 亚洲 欧美 国产 日韩 中文字幕| 人人爽人人添人人超| 久久综合狠狠综合久久激情| 精品人妻系列无码人妻漫画| 欧美精品国产aⅴ一区二区在线| 亚洲 综合 校园 欧美 制服| 韩国 日本 亚洲 国产 不卡| 免费拍拍拍网站| 国产精品久久久久久吹潮| 国产99视频精品免视看9| 亚洲欧美在线制服丝袜国产| 国产欧美va天堂在线观看视频下载 | 成人国产精品一区二区免费看| 久久99精品久久久久久水蜜桃 | 亚洲久久中文字幕www网站| 亚洲欧美日韩综合一区在线| 国产高清在线精品二区| 国产丰满麻豆videossexhd| 亚洲高清乱码午夜电影网 | 色v99在线影院| 蜜桃麻豆www久久国产sex| 国内精品视频一区二区三区| 国产av麻豆mag剧集| 男女做爽爽爽视频免费软件| 亚洲乱码日产精品bd在观看 | 高h纯肉无码视频在线观看| 蜜臀av综合网| 久久精品国产2020| 无码国产伦一区二区三区视频| 中文字幕一区二区三区精华液| 国产1卡2卡3卡4卡免费| 最新亚洲人成无码网站| 久久综合色之久久综合| 久久中文字幕乱码久久午夜| 婷婷五月综合色中文字幕| 正在播放老肥熟妇露脸| 人人澡人摸人人添| 永久中文字幕免费视频网站| 国产亚洲精品俞拍视频| 亚洲乱码无码永久不卡在线| 天天躁夜夜躁天干天干2020|