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  4. IFT81 Antibody

IFT81 Antibody

  • 中文名稱：
    IFT81兔多克隆抗體
  • 貨號(hào)：
    CSB-PA011079GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    IFT81
  • 別名：
    Carnitine deficiency associated expressed in ventricle 1 isoform 2 antibody; Carnitine deficiency-associated protein expressed in ventricle 1 antibody; CDV-1 antibody; CDV1 antibody; CDV1R antibody; Ift81 antibody; IFT81_HUMAN antibody; intraflagellar transport 81 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 81 homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human IFT81
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling.
  • 基因功能參考文獻(xiàn)：
    1. This represents the first report of mutations in IFT81 as a candidate gene for nonsyndromic retinal dystrophy, hence expanding the phenotype spectrum of IFT-B components. PMID: 28460050
    2. this study found that the two core intraflagellar transport proteins IFT74 and IFT81 form a tubulin-binding module and mapped the interaction to a calponin homology domain of IFT81 and a highly basic domain in IFT74. PMID: 23990561
    3. inconsistent expression levels of human CDV-1 and mouse Cdv-1 in heart implied that cardiac hypertrophy in human SCD might not be associated with the abnormal expression of CDV-1 PMID: 12549821
  • 亞細(xì)胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    IFT81 family
  • 組織特異性：
    Highly expressed in testis, moderately in ovary, heart, liver, skeletal muscle, kidney and pancreas, low in prostate, brain, placenta and lung and not detected in spleen, thymus, small intestine and colon. Isoform CDV-1R is abundantly expressed in testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14313

    OMIM: 605489

    KEGG: hsa:28981

    STRING: 9606.ENSP00000242591

    UniGene: Hs.528382



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