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IFT27 Antibody

  • 中文名稱：
    IFT27兔多克隆抗體
  • 貨號：
    CSB-PA874822LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA874822LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA874822LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IFT27 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IFT27
  • 別名：
    BBS19 antibody; Ift27 antibody; IFT27_HUMAN antibody; Intraflagellar transport 27 antibody; Intraflagellar transport protein 27 homolog antibody; Putative GTP binding protein RAY like antibody; Putative GTP-binding protein RAY-like antibody; Rab like protein 4 antibody; RAB member of RAS oncogene family like 4 antibody; Rab-like protein 4 antibody; RAYL antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，IFT27 Antibody (CSB-PA874822LA01HU)，的標記方式是Non-conjugated。對于IFT27 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA874822LB01HU IFT27 Antibody, HRP conjugated ELISA
    FITC CSB-PA874822LC01HU IFT27 Antibody, FITC conjugated
    Biotin CSB-PA874822LD01HU IFT27 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
  • 基因功能參考文獻：
    1. Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS gene (BBS19). PMID: 24488770
  • 相關疾?。?/div>
    Bardet-Biedl syndrome 19 (BBS19)
  • 亞細胞定位：
    Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 數據庫鏈接：

    HGNC: 18626

    OMIM: 615870

    KEGG: hsa:11020

    STRING: 9606.ENSP00000393541

    UniGene: Hs.415172



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