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  4. IFT172 Antibody

IFT172 Antibody

  • 中文名稱：
    IFT172兔多克隆抗體
  • 貨號：
    CSB-PA887019LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA887019LA01HU diluted at 1:400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA887019LA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of A549 cells with CSB-PA887019LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IFT172 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IFT172
  • 別名：
    IF172_HUMAN antibody; ift172 antibody; Intraflagellar transport 172 homolog (Chlamydomonas) antibody; Intraflagellar transport protein 172 homolog antibody; Osm 1 antibody; Selective LIM binding factor homolog antibody; SLB antibody; Wim antibody; Wimple homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Intraflagellar transport protein 172 homolog protein (1368-1502AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，IFT172 Antibody (CSB-PA887019LA01HU)，的標記方式是Non-conjugated。對于IFT172 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA887019LB01HU IFT172 Antibody, HRP conjugated ELISA
    FITC CSB-PA887019LC01HU IFT172 Antibody, FITC conjugated
    Biotin CSB-PA887019LD01HU IFT172 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
  • 基因功能參考文獻：
    1. This is the second report of IFT172 mutations in BBS patients validating IFT172 as the twentieth BBS gene (BBS20). PMID: 26763875
    2. Findings identified mutations in IFT172 that lead to a recessive form of non-syndromic retinitis pigmentosa and Bardet-Biedl syndrome and suggest that the primary IFT172 mutations alone are not sufficient to explain the wide range of phenotypes. PMID: 25168386
    3. We have identified defects in IFT172 as a cause of complex asphyxiating thoracic dystrophy and Mainzer-Saldino syndrome. PMID: 24140113
  • 相關疾?。?/div>
    Short-rib thoracic dysplasia 10 with or without polydactyly (SRTD10); Retinitis pigmentosa 71 (RP71)
  • 亞細胞定位：
    Cell projection, cilium. Note=Localized to the axoneme and around the base of the cilium.
  • 蛋白家族：
    IFT172 family
  • 數據庫鏈接：

    HGNC: 30391

    OMIM: 607386

    KEGG: hsa:26160

    STRING: 9606.ENSP00000260570

    UniGene: Hs.127401



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