在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IFT140 Antibody, HRP conjugated

  • 中文名稱:
    IFT140兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA842756LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) IFT140 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    IFT140
  • 別名:
    IFT140 antibody; KIAA0590 antibody; WDTC2 antibody; Intraflagellar transport protein 140 homolog antibody; WD and tetratricopeptide repeats protein 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Intraflagellar transport protein 140 homolog protein (1291-1462AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells.
  • 基因功能參考文獻:
    1. A maternally inherited homozygous biallelic mutation altering the exon 6 splice donor site in IFT140 gene causes Mainzer-Saldino syndrome. PMID: 28724397
    2. We provide the first description of an Opitz trigonocephaly C syndrome (OTCS) phenotype that appears to result from IFT140 mutations. The presentation of this patient is consistent with previous reports showing that OTCS already exhibited skeleletal and nonskeletal features of a ciliopathy PMID: 27874174
    3. Recessive IFT140 mutations cause a severe congenital retinal dystrophy with high hyperopia and often early photophilia. Developmental delay is common but not universal and not all patients have obvious extraocular findings. PMID: 26359340
    4. This study highlights the phenotype of nonsyndromic RP due to mutations in IFT140 with milder retinal dystrophy than that associated with the syndromic disease. PMID: 26968735
    5. Identification of IFT140 variants in multiple unrelated non-syndromic Leber congenital amaurosis and retinitis pigmentosa. PMID: 26216056
    6. Genetic analysis revealed both to harbor recessive mutations in IFT140, a cilium gene recently associated with the skeletal ciliopathy conorenal syndrome. PMID: 24698627
    7. present study strengthens the rationale for IFT140 screening in skeletal ciliopathy spectrum patients that have kidney disease and/or retinal dystrophy PMID: 23418020
    8. IFT140 mutations were identified in Mainzer-Saldino syndrome. IFT140 plays a role in proper development and function of ciliated cells. PMID: 22503633
    9. loss of Ift140 causes pronounced renal cystic disease and suggest that abnormalities in several different pathways may influence cyst progression. PMID: 22282595

    顯示更多

    收起更多

  • 相關疾病:
    Short-rib thoracic dysplasia 9 with or without polydactyly (SRTD9)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
  • 數據庫鏈接:

    HGNC: 29077

    OMIM: 266920

    KEGG: hsa:9742

    STRING: 9606.ENSP00000406012

    UniGene: Hs.389438



主站蜘蛛池模板: 国产精品成人久久电影| 人人超人人超碰超国产| 好了av第四综合无码久久| 欧美做爰性生交视频| 少妇愉情理伦片高潮日本| 国产 高清 无码 在线播放| 久9视频这里只有精品试看| 小宝极品内射国产在线| 人人妻人人澡人人爽人人dvd| 婷婷五月深爱憿情网| h人成在线看免费视频| 亚洲毛片αv无线播放一区| 国产一区二区三区乱码在线观看| 亚洲一区激情校园小说| 欲色影视天天一区二区色香欲| 中国老熟女重囗味hdxx| 92电影网午夜福利| 久久久这里只有精品10| 在线观看精品视频网站| 各种少妇正面bbw撒尿| 在线a视频网站| 白嫩无码人妻丰满熟妇啪啪区百度| 777米奇色狠狠俺去啦| 东京热无码av男人的天堂| 国产最新进精品视频| 永久黄网站免费视频性色| 偷拍农村老熟妇xxxxx7视频| 日日天干夜夜狠狠爱| 国产嫖妓风韵犹存对白| 在线 亚洲 国产 欧美| 无码免费h成年动漫在线观看 | 国产精品国产三级国产专区53| 亚洲第一网站男人都懂| 韩国 欧美 日产 国产精品| 人人妻人人澡人人爽精品欧美| 人人做人人爽人人爱| 中国性欧美videofree精品| 朋友的丰满人妻中文字幕| 欧美老人巨大xxxx做受视频 | 国产无遮挡裸体免费视频在线观看| 久久婷婷综合激情亚洲狠狠|