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  4. IDI2 Antibody

IDI2 Antibody

  • 中文名稱：
    IDI2兔多克隆抗體
  • 貨號：
    CSB-PA010995GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    IDI2
  • 別名：
    IDI2 antibody; Isopentenyl-diphosphate delta-isomerase 2 antibody; EC 5.3.3.2 antibody; Isopentenyl pyrophosphate isomerase 2 antibody; IPP isomerase 2 antibody; IPPI2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human IDI2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  • 基因功能參考文獻：
    1. The present findings suggest that IDI1 and IDI2 may be associated with the production of cholesterol metabolites in neurons, leading to alpha-synuclein aggregation during the process of Lewy body formation. PMID: 25950736
    2. Within the 40-kb region on 10p15.3 subtelomere, which harbours two genes encoding isopentenyl diphosphate isomerase 1 (IDI1) and IDI2, there was found a segmental copy-number gain in a large proportion of sporadic amyotrophic lateral sclerosis patients. PMID: 20955688
    3. IDI2 is expressed at high levels only in skeletal muscle, where it may be involved in the specialized production of isoprenyl diphosphates for the posttranslational modification of proteins. PMID: 14629038
    4. Enzyme kinetic analysis; both isozymes IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway; data suggest that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPARalpha PMID: 17202134
  • 亞細胞定位：
    Peroxisome.
  • 蛋白家族：
    IPP isomerase type 1 family
  • 組織特異性：
    Muscle-specific expression.
  • 數據庫鏈接：

    HGNC: 23487

    OMIM: 615389

    KEGG: hsa:91734

    STRING: 9606.ENSP00000277517

    UniGene: Hs.591325



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