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  4. IDH3G Antibody

IDH3G Antibody

  • 中文名稱：
    IDH3G兔多克隆抗體
  • 貨號：
    CSB-PA066473
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA066473(IDH3G Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA066473(IDH3G Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: A431 cells, mouse brain tissue, Primary antibody: CSB-PA066473(IDH3G Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    IDH3G
  • 別名：
    H IDHG antibody; IDH gamma antibody; IDH3G antibody; IDH3G_HUMAN antibody; Isocitrate dehydrogenase [NAD] subunit gamma antibody; Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial antibody; Isocitrate dehydrogenase 3 (NAD+) gamma antibody; Isocitric dehydrogenase antibody; Isocitric dehydrogenase subunit gamma antibody; mitochondrial antibody; NAD (H) specific isocitrate dehydrogenase gamma subunit antibody; NAD(+) specific ICDH antibody; NAD(+)-specific ICDH subunit gamma antibody; NAD+ specific ICDH antibody; OTTHUMP00000025984 antibody; OTTHUMP00000025985 antibody; OTTHUMP00000025987 antibody; OTTHUMP00000025988 antibody; OTTHUMP00000214764 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human IDH3G
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
  • 基因功能參考文獻：
    1. Aspartate-190 is a determinant of IDH gamma subunit affinity for the manganese (MnII) ion, as well as for nicotinamide-adenine dinucleotide (NAD), but is not directly required for the catalytic reaction. PMID: 17432878
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Isocitrate and isopropylmalate dehydrogenases family
  • 數據庫鏈接：

    HGNC: 5386

    OMIM: 300089

    KEGG: hsa:3421

    STRING: 9606.ENSP00000217901

    UniGene: Hs.410197



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