在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ID3 Antibody

  • 中文名稱:
    ID3兔多克隆抗體
  • 貨號:
    CSB-PA01959A0Rb
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunofluorescent analysis of Hela cells using CSB-PA01959A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ID3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    1R21 antibody; bHLHb25 antibody; Class B basic helix-loop-helix protein 25 antibody; DNA binding protein inhibitor ID 3 antibody; DNA-binding protein inhibitor ID-3 antibody; HEIR 1 antibody; HEIR1 antibody; Helix loop helix protein HEIR 1 antibody; Helix loop helix protein HEIR1 antibody; Helix-loop-helix protein HEIR-1 antibody; HLH642 antibody; ID 3 antibody; ID like protein inhibitor HLH 1R21 antibody; ID like protein inhibitor HLH 462 antibody; ID-like protein inhibitor HLH 1R21 antibody; ID3 antibody; ID3_HUMAN antibody; Inhibitor of DNA binding 3 antibody; Inhibitor of DNA binding 3 dominant negative helix loop helix protein antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human DNA-binding protein inhibitor ID-3 protein (27-99AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,ID3 Antibody (CSB-PA01959A0Rb),的標記方式是Non-conjugated。對于ID3 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA01959B0Rb ID3 Antibody, HRP conjugated ELISA
    FITC CSB-PA01959C0Rb ID3 Antibody, FITC conjugated
    Biotin CSB-PA01959D0Rb ID3 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.
  • 基因功能參考文獻:
    1. This review will discuss the current understanding of ID3 in excess fat accumulation and the potential for Estrogenic Endocrine Disruptors to influence susceptibility to obesity or metabolic disorders via ID3 signaling PMID: 29507860
    2. Taken together, we found that Id3+ and CTLA-4+ endometrial cells were significantly higher in women with repeated implantation failure and recurrent miscarriage, suggesting the negative roles of these angiogenesis and immune tolerance markers involving in regulating endometrium receptivity. PMID: 28224680
    3. The interactions between ID3 and the DNA damage mediator protein MDC1 suggest that ID3 participates in the DNA damage signaling pathway to maintain genomic stability. PMID: 29026069
    4. Immunohistochemical detection of inhibitor of DNA binding 3 mutational variants in mature aggressive B-cell lymphoma. PMID: 26992947
    5. The results of the present study revealed that overexpression of Id3 may serve as a novel strategy for inhibiting cisplatinsensitive lung cancer. PMID: 27176047
    6. Upon Id3 transfection, A549 cells displayed decreased migratory and invasive capabilities, however, co-transfection of miRId3 and Id3 into A549 cells reversed the Id3-induced inhibitions of migratory and invasive capabilities. PMID: 26384138
    7. ID3 has a role in the acquisition of molecular stem cell-like signature in microvascular endothelial cells PMID: 25665868
    8. our data provide evidence that ID3 may play a critical role in regulating vascular endothelial cell survival and development of microvascular lesions induced by persistent environmental pollutants such as PCB153. PMID: 25090023
    9. ID3 plays a potential role in the underlying regulatory mechanisms of metabolic health in human obesity. [Review] PMID: 25239768
    10. Epigenetic changes in ID3, in combination with experiences of maltreatment, may confer risk for depression in children. PMID: 24655651
    11. Data indicate association of inhibitor of differentiation 3 (ID3) single nucleotide polymorphism rs11574 directly with coronary artery pathology. PMID: 24603695
    12. Importantly, the distinct ID3 expression patterns in acute leukemias (AL) indicate a specific deregulation of ID3 in the various types of AL and may support subtyping of AL. PMID: 24292846
    13. the combined immunohistochemical detection of VPREB3 and ID3 is applicable to the routine diagnostic in case of mature aggressive B-cell lymphomas. PMID: 24493312
    14. ID3 mutations are recurrent events in double-hit B-cell lymphomas. PMID: 24222112
    15. High ID3 expression is associated with medulloblastoma seeding and is a poor prognostic factor, especially in patients with Group 4 tumors PMID: 23768125
    16. The findings suggested that cooperation between ID3 inactivation and immunoglobulin-MYC gene translocation is a hallmark of Burkitt lymphomagenesis. PMID: 23143595
    17. Overexpression of Id3 markedly promoted the proliferation and invasive capacity of MCF-7 cells; however, these effects were significantly suppressed by the overexpression of FHL2. PMID: 22882857
    18. Overexpression of Id3 triggered apoptosis in A549 lung adenocarcinoma cells, implicating Id3 in negative control of tumor growth. PMID: 22151756
    19. EGFR-AKT-Smad signaling promotes formation of glioma stem-like cells and tumor angiogenesis by ID3-driven cytokine induction. PMID: 21975932
    20. The ID3 protein is expressed in prostate cancer, and is elevated with the increase of Gleason score. PMID: 21837949
    21. the data establish dysregulation of the Id/bHLH axis as an early and sustained feature of ductal pathogenesis PMID: 21498546
    22. The level of Id-3 protein expression was associated with the malignant potential of gastric tumors. PMID: 20080245
    23. ID3 plays a role as an apoptosis inducer in response to X-ray irradiation via the regulation of endogenous beta-catenin level. PMID: 21030215
    24. In serum samples of lung cancer patients, galectin 1-mediated Id3 induces expression of interleukin (IL)-10 in functionally altered signal pathways of monocytes and monocyte-derived dendritic cells. PMID: 21191065
    25. Results provide novel evidence that Id3 is an atheroprotective factor and link a common SNP in the human ID3 gene to loss of Id3 function and increased carotid intima-media thickness. PMID: 20185798
    26. nuclear Id protein acts by sequestering pools of transiently diffusing bHLH protein to prevent reassociation with chromatin domains PMID: 12952978
    27. Fluvastatin did not regulate p21 and p27, but down-regulated Id3 and p53 slightly. PMID: 15370294
    28. Overexpression of Id3 enhances expression of ICAM-1 and E-selectin, and induces angiogenic processes such as transmigration, matrix metalloproteinase-2 and -9 expression, and tube formation in cultured vascular endothelial cells. PMID: 15494533
    29. ultraviolet radiation-induced apoptosis of immortalized keratinocytes is at least in part due to Id3 upregulation in these cells PMID: 16449966
    30. estrogen-induced tube formation in vascular endothelial cells requires the presence of Id3, a member of the helix-loop-helix family of transcriptional factors and estrogen increases Id3 phosphorylation via a redox-dependent process PMID: 18281048
    31. RhoA/Rho-associated kinase signaling plays positive and negative roles in myogenic differentiation, mediated by MRTF-A/Smad-dependent transcription of the Id3 gene in a differentiation stage-specific manner PMID: 18477564
    32. There is a mechanism whereby reactive oxygen species upregulation of Id3 relieves repression of bax via E-box-binding factors. PMID: 19054058
    33. RNA interference demonstrated that Id3 regulates differentiation and cell cycle (increased Neuro-D6 and p21 mRNA) in neuroblastoma cells PMID: 19477940

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 組織特異性:
    Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5362

    OMIM: 600277

    KEGG: hsa:3399

    STRING: 9606.ENSP00000363689

    UniGene: Hs.76884



主站蜘蛛池模板: 麻豆一区二区99久久久久| 日韩成人极品在线内射3p蜜臀 | 国产成人无码一区二区三区在线 | 51久久成人国产精品麻豆| 新版资源天堂中文| 亚洲aⅴ综合色区无码一区| 色多多成视频人在线观看| 国产最新av在线播放不卡| 在线观看无码av网址| 人人超碰人人爱超碰国产 | 亚洲日本一区二区三区在线| 男人的天堂在线视频| 中文字幕乱码中文乱码51精品| 四虎亚洲欧美成人网站| 女人夜夜春高潮爽a∨片传媒 | 7777精品伊人久久久大香线蕉| 亚洲三区在线观看内射后入| 美女裸奶100%无遮挡免费网站 | 国产乱子伦一区二区三区=| 免费吃奶摸下激烈视频| 一区二区三区中文字幕| 影音先锋人妻每日资源站| 最近中文字幕mv在线视频2018| 久久无码专区国产精品| 毛片无码一区二区三区a片视频| 乱码午夜-极品国产内射| 国产精品人妻久久毛片高清无卡| 九九久久精品国产波多野结衣| 国产欧美va欧美va香蕉在线| 麻豆精品导航| 亚洲熟女精品中文字幕| 国产偷窥盗摄一区二区| 欧美丰满熟妇多毛xxxxx| 国产人与禽zoz0性伦多活几年| 国产乱子伦视频一区二区三区 | 少妇特黄a一区二区三区| 久久不见久久见免费影院www日本| 国产精品亚洲专区无码老司国 | 99re在线播放| 日产电影一区二区三区| 午夜福利电影网站鲁片大全|