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Your Good Partner in Biology Research

ICE1 Antibody, Biotin conjugated

  • 中文名稱:
    ICE1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA897466LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ICE1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ICE1
  • 別名:
    K0947_HUMAN antibody; KIAA0947 antibody; Uncharacterized protein KIAA0947 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies.
  • 基因功能參考文獻:
    1. The results indicate that p53 interferes with the interaction between ELL/EAF and ICE1 and represses transcription of small nuclear RNA genes by Pol II. PMID: 27268141
    2. Multigenerational autosomal dominant inheritance of 5p chromosomal deletions resulting in Cri-du-Chat Syndrome with SEMA5A, CTNND2, and ICE1 deficiencies has been described. PMID: 26601658
  • 亞細胞定位:
    Nucleus. Nucleus, Cajal body.
  • 蛋白家族:
    ICE1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 29154

    KEGG: hsa:23379

    STRING: 9606.ENSP00000296564

    UniGene: Hs.449296



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