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ICAM5 Antibody

  • 中文名稱:
    ICAM5兔多克隆抗體
  • 貨號:
    CSB-PA010953GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ICAM5
  • 別名:
    ICAM5 antibody; TLCN antibody; TLNIntercellular adhesion molecule 5 antibody; ICAM-5 antibody; Telencephalin antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ICAM5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
  • 基因功能參考文獻:
    1. Here the authors identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent entry of enterovirus D68. PMID: 27923705
    2. ICAM5 V301I and rs281439 variants may contribute to the susceptibility of breast cancer. [Meta-analysis] PMID: 23079714
    3. A specific microenvironment facilitating ARF6-mediated mobilization of TLN that contributes to promotion of dendritic spine development. PMID: 22781129
    4. study does not confirm association between ICAM 5 V3001 polymorphism and breast cancer risk PMID: 16434609
    5. ICAM-5 is involved in immune privilege of the brain and acts as an anti-inflammatory agent. PMID: 18223167

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  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Immunoglobulin superfamily, ICAM family
  • 組織特異性:
    Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
  • 數據庫鏈接:

    HGNC: 5348

    OMIM: 601852

    KEGG: hsa:7087

    STRING: 9606.ENSP00000221980

    UniGene: Hs.465862



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