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HTR1F Antibody

  • 中文名稱:
    HTR1F兔多克隆抗體
  • 貨號:
    CSB-PA004147
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of COS7 cells using SR-1F Polyclonal Antibody
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    HTR1F; HTR1EL; 5-hydroxytryptamine receptor 1F; 5-HT-1F; 5-HT1F; Serotonin receptor 1F
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat,Monkey
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human SR-1F.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
  • 基因功能參考文獻(xiàn):
    1. Supporting this model, pharmacological activation of 5-HT1F receptors reduces glucagon secretion and has hypoglycemic effects in diabetic mice. Thus, modulation of serotonin signaling in the islet represents a drug intervention opportunity PMID: 28009296
    2. 5-HT6 show no striking effects on executive function in the Chinese Han population. PMID: 21457069
  • 亞細(xì)胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5292

    OMIM: 182134

    KEGG: hsa:3355

    STRING: 9606.ENSP00000322924

    UniGene: Hs.248136



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