在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HSPB7 Antibody, HRP conjugated

  • 中文名稱:
    HSPB7兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA10979B0Rb
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) HSPB7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HSPB7
  • 別名:
    Cardiovascular heat shock protein antibody; cvHsp antibody; DKFZp779D0968 antibody; FLJ32733 antibody; Heat shock 27kda protein family member 7 antibody; Heat shock protein beta 7 antibody; Heat shock protein beta-7 antibody; Hsp25 2 antibody; HspB7 antibody; HSPB7_HUMAN antibody; Hypothetical protein flj34956 antibody; RP11-5P18.6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Heat shock protein beta-7 protein (1-170AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Loss of Hspb7 in zebrafish or human cardiomyocytes stimulated autophagic pathways and expression of the sister gene encoding Hspb5. Inhibiting autophagy caused FilaminC aggregation in HSPB7 mutant human cardiomyocytes and developmental cardiomyopathy in hspb7 mutant zebrafish embryos. PMID: 29331499
    2. our findings characterize HSPB7 as an intercalated disc protein and suggest it has an essential role in maintaining intercalated disc integrity and conduction function in the adult heart. PMID: 28827800
    3. Patients with central sleep apnea and congestive heart failure had higher T allele frequencies in the HSPB7 gene. PMID: 27441470
    4. HSPB7 loci is associated in the pathophysiologuy of ischemic heart failure. PMID: 25889438
    5. Results imply that HSBP7 is likely to be a tumor suppressor gene regulated by p53 and its downregulation by hypermethylation may play a critical role in renal carcinogenesis. PMID: 24585183
    6. HSPB7 is a potential early biomarker after MI and serves as an independent risk factor of ACS in patients with acute chest pain. PMID: 22785082
    7. Data show a significant association between a SNP in HSPB7 gene (rs1739843, minor allele frequency 39%) and idiopathic DCM. PMID: 20975947
    8. The rs1738943 shows that although this SNP is located within HSPB7, it resides in a block of high LD that spans HSPB7 and a nearby gene, CLCNKA, which encodes a voltage-sensitive chloride channel expressed mainly in the kidney. PMID: 20124441
    9. Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease. PMID: 20038796
    10. HSPB7 constitutively localized to SC35 splicing speckles, driven by its N-terminus. Unlike HSPB1 and HSPB5, that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding. PMID: 19464326

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • 蛋白家族:
    Small heat shock protein (HSP20) family
  • 組織特異性:
    Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.
  • 數據庫鏈接:

    HGNC: 5249

    OMIM: 610692

    KEGG: hsa:27129

    STRING: 9606.ENSP00000310111

    UniGene: Hs.502612



主站蜘蛛池模板: 先锋人妻无码av电影| 成人内射国产免费观看| 一本色道无码道在线观看| 国产在线无码视频一区二区三区| 亚洲国产成人一区二区三区| 毛多水多www偷窥小便| 亚洲国产精品一区二区www| 少女韩国电视剧在线观看完整| 国产日韩欧美亚洲精品中字| 中文人妻熟妇乱又伦精品| 亚洲爆乳aaa无码专区| 插我一区二区在线观看| 亚洲精品久久区二区三区蜜桃臀| 人妻少妇精品视频无码专区| 中文字幕人妻熟在线影院| 一个人看的www片免费高清视频| 精品人妻无码一区二区三区抖音| 亚洲日韩在线中文字幕综合 | 2012中文字幕在线视频| 337p日本欧洲亚洲大胆艺术图| 少妇私密推油呻吟在线播放| 巨大黑人极品videos精品| 亚洲妇女行蜜桃av网网站| 色偷偷偷久久伊人大杳蕉| 国产精品一区二区熟女不卡| 日韩一区二区三区精品| 全部露出来毛走秀福利视频| 97色精品视频在线观看| 人妻无码久久精品人妻| 亚洲-av-无限看| 欧美日韩一本的免费高清视频| 狠狠色色综合网站| 日本最新免费二区三区| 一区二区三区高清日本vr| 欲色欲色天天天www| 无码人妻精品一区二区三区9厂 | 欧美品无码一区二区三区在线蜜桃| 久久一卡二卡三卡四卡| 中国内地毛片免费高清| 国产人妻高清国产拍精品| 国内少妇高潮嗷嗷叫在线播放 |