在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HSPA6 Antibody
  • 中文名稱：
    HSPA6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA863082HA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: HSPA6 antibody at 2µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: A431 whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 72 kDa
      Observed band size: 72 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HSPA6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Heat shock 70 kDa protein 6 antibody; Heat shock 70 kDa protein B' antibody; Heat shock 70 kDa protein B'' antibody; heat shock 70kD protein 6 (HSP70B') antibody; Heat shock 70kDa protein 6 antibody; HSP70B' antibody; HSP70B-Prime antibody; HSP76_HUMAN antibody; HSPA6 antibody; OTTHUMP00000032372 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Heat shock 70 kDa protein 6 protein (1-637AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，HSPA6 Antibody (CSB-PA863082HA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于HSPA6 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA863082HB01HU HSPA6 Antibody, HRP conjugated ELISA
    FITC CSB-PA863082HC01HU HSPA6 Antibody, FITC conjugated
    Biotin CSB-PA863082HD01HU HSPA6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release.
  • 基因功能參考文獻(xiàn)：
    1. during recovery from neuronal stress, HSPA6 localized with perispeckles that have been characterized as transcription sites; the stress-induced association of HSPA6 with perispeckles displayed the greatest dynamism compared to the interaction of HSPA6 or HSPA1A with other stress-sensitive cytoplasmic and nuclear structures; this suggests involvement of HSPA6 in recovery of neurons from cellular stress PMID: 27527722
    2. In vivo efficacy experiments with HSPA6 siRNA and MFH were performed using the A2780cp20 and HeyA8 ovarian cancer mouse models. A significantly reduction in tumor growth rate was observed with combination therapy. PES and MFH efficacy were also evaluated in the HeyA8 intraperitoneal tumor model, and resulted in robust antitumor effects. PMID: 28223424
    3. measurable HSP70B' was not associated with graft versus host disease following allogeneic hematopoietic cell transplantation PMID: 27020764
    4. endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B') in human arterial smooth muscle cells PMID: 26656590
    5. Data indicate that heat shock protein 90kD(HSP90) inhibition induces heat shock 70kD protein 6 (HSP70B') expression. PMID: 25957766
    6. HSPA6 regulation by TNIP1 occurs in promoter regions lacking binding sites for known TNIP1-repressed transcription factors PMID: 25447897
    7. Hsp70B' also formed complexes with Hsp40 suggesting a common co-chaperone for HSP70 family members. PMID: 20084477
    8. Heat shock protein 70B' (HSP70B') expression and release in response to human oxidized low density lipoprotein immune complexes in macrophages. PMID: 20348092
    9. These findings are likely to be important in pathological conditions in which Hsp70B' contributes to cell survival. PMID: 18229458
    10. Hsp70B' expressed on colon cells after proteasome inhibition was most closely related to Hsp72. They shared 100% AA identity in the peptide-binding region but differed in the lid and C-terminal domains.Hsp70B' appeared to have diverged recently. PMID: 18347947

    顯示更多

    收起更多

  • 蛋白家族：
    Heat shock protein 70 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5239

    OMIM: 140555

    KEGG: hsa:3310

    STRING: 9606.ENSP00000310219

    UniGene: Hs.654614



主站蜘蛛池模板： 欧美孕妇变态孕交粗暴| 亚洲精品国产一区二区在线观看| 亚洲国产精品无码av| 噜噜高清欧美内射短视频| 日本中文一区二区三区亚洲| 性少妇无码播放| 国产高清av首播原创麻豆| 羞羞视频在线观看| 久久久久国色av免费看图片| 国产亚洲另类无码专区| 国产亚洲精品第一综合麻豆| 无码aⅴ精品一区二区三区| 亚洲a∨无码一区二区| 久久久无码精品午夜| 国产成人8x人网站视频| 久久精品国自产拍| 疯狂的欧美乱大交| 国产乱码精品一品二品| 黑人大战中国av女叫惨了| 天天躁夜夜躁狠狠躁2021 | 日韩精品无码一本二本三本| 国产在线码观看超清无码视频| 超清无码波多野吉衣中文| 欧美大成色www永久网站婷| 中文人妻无码一区二区三区| 成人精品一区二区三区电影免费| 欧美亚洲国产手机在线有码| 国产乱子夫妻xx黑人xyx真爽| 中文字幕乱码人妻一区二区三区| 欧美成人精品三级一二三在线观看| 奇米777狠狠色噜噜狠狠狠| 欧美日韩一卡2卡三卡4卡 乱码欧美孕交 | 国产乱人伦偷精品视频| 夜夜高潮夜夜爽高清视频| 亚洲的天堂av无码| 国产成人无码一区二区在线播放| 高大丰满欧美熟妇hd| 麻豆国产人妻欲求不满| 久久国产人妻一区二区免费| 精品无码专区毛片| 日本伊人色综合网|