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  4. HS1BP3 Antibody

HS1BP3 Antibody

  • 中文名稱：
    HS1BP3兔多克隆抗體
  • 貨號：
    CSB-PA703623ESR1HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HS1BP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HS1BP3
  • 別名：
    ETM2 antibody; FLJ14249 antibody; H1BP3_HUMAN antibody; HCLS1 binding protein 3 antibody; HCLS1-binding protein 3 antibody; HS1 binding protein 3 antibody; HS1 BP3 antibody; HS1-binding protein 3 antibody; Hs1bp3 antibody; HSP1BP-3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human HCLS1-binding protein 3 protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    May be a modulator of IL-2 signaling.
  • 基因功能參考文獻(xiàn)：
    1. HS1BP3 is localized to ATG16L1- and ATG9-positive autophagosome precursors and we show that HS1BP3 binds phosphatidic acid (PA) through its PX domain. Furthermore, we find the total PA content of cells to be significantly upregulated in the absence of HS1BP3. PMID: 28004827
    2. Results suggest that HS1BP3 regulates apoptosis via HS1 and stimulates AP-1-mediated transcription. PMID: 21699750
    3. The 828C-->G mutation causes a substitution of a glycine for an alanine residue in the HS1-BP3 protein. It was found in 2 unrelated patients with familial essential tremor. PMID: 15699368
    4. HS1PB3 protein is mutated in essential tremor combined with Parkinson disease. PMID: 16116142
    5. Results do not support a role for these DRD3 and HS1BP3 variants in PD. PMID: 19524641

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  • 數(shù)據(jù)庫鏈接：

    HGNC: 24979

    OMIM: 609359

    KEGG: hsa:64342

    STRING: 9606.ENSP00000305193

    UniGene: Hs.531785



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