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HOXC9 Antibody, HRP conjugated

  • 中文名稱:
    HOXC9兔多克隆抗體, HRP偶聯(lián)
  • 貨號(hào):
    CSB-PA010679LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HOXC9 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HOXC9
  • 別名:
    Homeo box C9 antibody; Homeobox C9 antibody; Homeobox protein Hox C9 antibody; Homeobox protein Hox-3B antibody; Homeobox protein Hox-C9 antibody; Hox 3B antibody; HOX3 antibody; HOX3B antibody; Hoxc9 antibody; HXC9_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Homeobox protein Hox-C9 protein (18-260AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能參考文獻(xiàn):
    1. HOXC9 knockdown inhibited the metastasis and stem cell-like phenotype of GC cells without significant effects on cell proliferation as a direct target of miR-26a. PMID: 30205370
    2. downregulation of HOXC9 releases its transcriptional inhibition of DAPK1, resulting in the activation of the DAPK1-Beclin1 pathway, which induces autophagy in glioblastoma cells PMID: 26582930
    3. HOXC9 and HOXC10 may play an important role in the development of obesity, adverse fat distribution, and subsequent alterations in whole-body metabolism and adipose tissue function. PMID: 26647900
    4. Results provide a set of the essential genes in the miR-193a-3p/HOXC9/DNA damage response/oxidative stress pathway axis as the diagnostic targets for the guided anti-bladder cancer chemotherapy. PMID: 25444900
    5. HOXC9 coordinates diverse cellular processes associated with differentiation by directly activating and repressing the transcription of distinct sets of genes. PMID: 24274069
    6. HoxC9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. PMID: 23579273
    7. We did not find any potential pathological mutations in the Hoxc9 gene among Chinese patients with congenital heart disease. PMID: 22106857
    8. The data identify HOXC9 as an endothelial cell active transcriptional repressor promoting the resting, antiangiogenic endothelial cell phenotype in an interleukin 8-dependent manner PMID: 21493894
    9. HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma. PMID: 21507931
    10. Up-regulation of HOXC9 was detected in a set of 54 astrocytomas of different grades and significantly associated with malignancy. PMID: 17588684
    11. Methylated state of this set of genes may be more specific to the late rather than the early stage of NSCLC. PMID: 19506903

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  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Abd-B homeobox family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 5130

    OMIM: 142971

    KEGG: hsa:3225

    STRING: 9606.ENSP00000302836

    UniGene: Hs.658823



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